R Mousavi, D Lobo - npj Systems Biology and Applications, 2024 - nature.com
Gene regulatory mechanisms (GRMs) control the formation of spatial and temporal expression patterns that can serve as regulatory signals for the development of complex …
Cellvibrio japonicus is a saprophytic bacterium proficient at environmental polysaccharide degradation for carbon and energy acquisition. Genetic, enzymatic, and structural …
R Mousavi, SH Konuru, D Lobo - Briefings in Bioinformatics, 2021 - academic.oup.com
Reverse engineering mechanistic gene regulatory network (GRN) models with a specific dynamic spatial behavior is an inverse problem without analytical solutions in general …
A Hari, A Zarrabi, D Lobo - NAR Genomics and Bioinformatics, 2024 - academic.oup.com
Numerous methods exist to produce and refine genome-scale metabolic models. However, due to the use of incompatible identifier systems for metabolites and reactions, computing …
Numerous methods exist to produce and refine genome-scale metabolic models. However, due to the use of incompatible identifier systems for metabolites and reactions, computing …
Mathematical models formally and precisely represent biological mechanisms with complex dynamics. To understand the possible behaviors of such systems, phase portrait diagrams …
Genetic and metabolic engineering has made it possible to use microbial organisms as systems that can be engineered for various applications such as bio-product generation and …