A General Model for Biofilm-Driven Microbial Electrosynthesis of Carboxylates From CO2

O Cabau-Peinado, AJJ Straathof… - Frontiers in Microbiology, 2021 - frontiersin.org
Up to now, computational modeling of microbial electrosynthesis (MES) has been
underexplored, but is necessary to achieve breakthrough understanding of the process …

Automatic design of gene regulatory mechanisms for spatial pattern formation

R Mousavi, D Lobo - npj Systems Biology and Applications, 2024 - nature.com
Gene regulatory mechanisms (GRMs) control the formation of spatial and temporal
expression patterns that can serve as regulatory signals for the development of complex …

Microbe Profile: Cellvibrio japonicus: living the sweet life via biomass break-down

JG Gardner - Microbiology, 2024 - microbiologyresearch.org
Cellvibrio japonicus is a saprophytic bacterium proficient at environmental polysaccharide
degradation for carbon and energy acquisition. Genetic, enzymatic, and structural …

Inference of dynamic spatial GRN models with multi-GPU evolutionary computation

R Mousavi, SH Konuru, D Lobo - Briefings in Bioinformatics, 2021 - academic.oup.com
Reverse engineering mechanistic gene regulatory network (GRN) models with a specific
dynamic spatial behavior is an inverse problem without analytical solutions in general …

mergem: merging, comparing, and translating genome-scale metabolic models using universal identifiers

A Hari, A Zarrabi, D Lobo - NAR Genomics and Bioinformatics, 2024 - academic.oup.com
Numerous methods exist to produce and refine genome-scale metabolic models. However,
due to the use of incompatible identifier systems for metabolites and reactions, computing …

mergem: merging and comparing genome-scale metabolic models using universal identifiers

A Hari, D Lobo - bioRxiv, 2022 - biorxiv.org
Numerous methods exist to produce and refine genome-scale metabolic models. However,
due to the use of incompatible identifier systems for metabolites and reactions, computing …

Automatic generation of interactive multidimensional phase portraits

OO Ogunsan, D Lobo - bioRxiv, 2022 - biorxiv.org
Mathematical models formally and precisely represent biological mechanisms with complex
dynamics. To understand the possible behaviors of such systems, phase portrait diagrams …

Novel Systems Biology Methods for the Analysis, Optimization, and Visualization of Kinetic and Genome-Scale Stoichiometric Models

A Hari - 2022 - search.proquest.com
Genetic and metabolic engineering has made it possible to use microbial organisms as
systems that can be engineered for various applications such as bio-product generation and …