Small proteins comprising less than 100 amino acids have been often ignored in bacterial
genome annotations. About 10 years ago, focused efforts started to investigate whole …

Highlights•C. difficile (CD) is an emerging human enteropathogen.•Recent advances
suggest a key role of RNAs in CD and its interplay with phages.•CD prophages encode …

The ability to form a dormant spore is essential for the survival of the anaerobic pathogen,
Clostridioides difficile, outside of the mammalian gastrointestinal tract. The initiation of …

The gram-positive human pathogen Clostridioides difficile has emerged as the leading
cause of antibiotic-associated diarrhea. However, little is known about the bacterium's …

The obligate anaerobic, enteric pathogen Clostridioides difficile persists in the intestinal tract
by forming antibiotic‐resistant endospores that contribute to relapsing and recurrent …

Much of our current knowledge about cellular RNA–protein complexes in bacteria is derived
from analyses in gram-negative model organisms, with the discovery of RNA-binding …

SR1 is a dual-function sRNA from Bacillus subtilis. It inhibits translation initiation of ahrC
mRNA encoding the transcription activator of the arginine catabolic operons. Base-pairing is …

Regulatory RNAs have emerged as ubiquitous gene regulators in all bacterial species
studied to date. The combination of sequence-specific RNA interactions and malleable RNA …

Bacterial small regulatory RNAs (sRNAs) are key regulators of gene expression in many
processes related to adaptive responses. A multitude of sRNAs have been identified in …

Clostridioides difficile is the leading cause of healthcare-associated diarrhea in
industrialized countries. Many questions remain to be answered about the mechanisms …