Genome‐wide association studies (GWAS) and whole‐exome sequencing (WES) generate
massive amounts of genomic variant information, and a major challenge is to identify which …

Clinical and pre-clinical evidence has implicated neuregulin 1 (NRG1) as a critical
component in the pathophysiology of schizophrenia. However, the arrival of the genome …

While GWAS identify many disease-associated SNPs, using them to decipher disease
mechanisms is hindered by the difficulty in mapping SNPs to genes. Most SNPs are in non …

Myalgic encephalomyelitis, also known as chronic fatigue syndrome or ME/CFS, is a
multifactorial and debilitating disease that has an impact on over 4 million people in the …

Soybean is a major source of protein for human consumption and animal feed. Releasing
new cultivars with high nutritional value is one of the major goals in soybean breeding. To …

While hundreds of loci have been identified as reflecting strong-positive selection in human
populations, connections between candidate loci and specific selective pressures often …

In genetics, pleiotropy describes the genetic effect of a single gene on multiple phenotypic
traits. A common approach is to analyze the phenotypic traits separately using univariate …

A primary challenge in understanding disease biology from genome-wide association
studies (GWAS) arises from the inability to directly implicate causal genes from association …

We previously reported the findings from a genome-wide association study of the response
of maximal oxygen uptake (V̇o2max) to an exercise program. Here we follow up on these …

Insights into type 1 diabetes provided by genetic analyses : Current Opinion in Endocrinology,
Diabetes and Obesity Insights into type 1 diabetes provided by genetic analyses : Current …