In terrestrial vertebrates, bone tissue constitutes the 'osteoimmune'system, which functions
as a locomotor organ and a mineral reservoir as well as a primary lymphoid organ where …

Adult haematopoietic stem cells (HSCs) mainly reside in the bone marrow, where stromal
and haematopoietic cells regulate their function. The steady state HSC niche has been …

Coccidiosis is an economically significant disease in the global poultry industry, but little is
known about the mechanisms of bone defects caused by coccidiosis; thus, the study focused …

The objective of this study was to evaluate the impact of coccidiosis on bone quality and
antioxidant status in the liver and bone marrow of broiler chickens. A total of 360 13-day old …

Systemic inflammation mediated by Plasmodium parasites is central to malaria disease and
its complications. Plasmodium parasites reside in erythrocytes and can theoretically reach …

Monocytes are innate immune cells essential for host protection against malaria. Upon
activation, monocytes function to help reduce parasite burden through phagocytosis …

Highlights•Chloroquine/hydroxychloroquine is an old anti-malarial drug belongs to 4-
aminoquinolines.•Chloroquine has additional anti-virus, anti-bacteria, anti-protozoan, anti …

Objective This paper presents the current state of the art in the investigation of past malaria
by providing an extensive review of previous studies and identifying research possibilities …

Increasing knowledge on inflammatory mediators and bone metabolism highlights the
relationship between inflammation and bone disease. During acute illness, inflammatory …

Severe infections are a major stress on haematopoiesis, where the consequences for
haematopoietic stem cells (HSCs) have only recently started to emerge. HSC function …