Pyrazinamide resistance in Mycobacterium tuberculosis: Review and update

M Njire, Y Tan, J Mugweru, C Wang, J Guo… - Advances in medical …, 2016 - Elsevier
The global control and management of tuberculosis (TB) is faced with the formidable
challenge of worsening scenarios of drug-resistant disease. Pyrazinamide (PZA) is an …

Current and future technologies for the detection of antibiotic-resistant bacteria

D Yamin, V Uskoković, AM Wakil, MD Goni… - Diagnostics, 2023 - mdpi.com
Antibiotic resistance is a global public health concern, posing a significant threat to the
effectiveness of antibiotics in treating bacterial infections. The accurate and timely detection …

A robust SNP barcode for typing Mycobacterium tuberculosis complex strains

F Coll, R McNerney, JA Guerra-Assunção… - Nature …, 2014 - nature.com
Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an
important factor in pathogenesis that may affect virulence, transmissibility, host response …

Role of pncA and rpsA Gene Sequencing in Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis Isolates from Southern China

Y Tan, Z Hu, T Zhang, X Cai, H Kuang… - Journal of clinical …, 2014 - Am Soc Microbiol
We sequenced pncA and rpsA genes plus flanking regions of 161 Mycobacterium
tuberculosis isolates and found 10 new pncA and 3 novel rpsA mutations in pyrazinamide …

Genome-wide Mycobacterium tuberculosis variation (GMTV) database: a new tool for integrating sequence variations and epidemiology

EN Chernyaeva, MV Shulgina, MS Rotkevich… - BMC genomics, 2014 - Springer
Background Tuberculosis (TB) poses a worldwide threat due to advancing multidrug-
resistant strains and deadly co-infections with Human immunodeficiency virus. Today large …

Emerging rapid resistance testing methods for clinical microbiology laboratories and their potential impact on patient management

H Frickmann, WO Masanta… - BioMed research …, 2014 - Wiley Online Library
Atypical and multidrug resistance, especially ESBL and carbapenemase expressing
Enterobacteriaceae, is globally spreading. Therefore, it becomes increasingly difficult to …

Mycoplasmas and their antibiotic resistance: The problems and prospects in controlling infections

OA Chernova, ES Medvedeva… - Acta Naturae …, 2016 - cyberleninka.ru
The present review discusses the problem of controlling mycoplasmas (class Mollicutes), the
smallest of self-replicating prokaryotes, parasites of higher eukaryotes, and main …

The essential role of SepF in mycobacterial division

S Gola, T Munder, S Casonato… - Molecular …, 2015 - Wiley Online Library
Mycobacteria lack several of the components that are essential in model systems as E
scherichia coli or B acillus subtilis for the formation of the divisome, a ring‐like structure …

Shrinking the FadE Proteome of Mycobacterium tuberculosis: Insights into Cholesterol Metabolism through Identification of an α2β2 Heterotetrameric Acyl Coenzyme …

MF Wipperman, M Yang, ST Thomas… - Journal of …, 2013 - Am Soc Microbiol
The ability of the pathogen Mycobacterium tuberculosis to metabolize steroids like
cholesterol and the roles that these compounds play in the virulence and pathogenesis of …

Complete Genome Sequencing of Mycobacterium bovis SP38 and Comparative Genomics of Mycobacterium bovis and M. tuberculosis Strains

CK Zimpel, PE Brandão, AF de Souza Filho… - Frontiers in …, 2017 - frontiersin.org
Mycobacterium bovis causes bovine tuberculosis and is the main organism responsible for
zoonotic tuberculosis in humans. We performed the sequencing, assembly and annotation …