Arachidonic acid (AA) pathway, a metabolic process, plays a key role in carcinogenesis.
Hence, AA pathway metabolic enzymes phospholipase A 2 s (PLA 2 s), cyclooxygenases …

Abstract Nigella sativa (N. sativa), which belongs to the botanical family of Ranunculaceae,
is a widely used medicinal plant all over the world. N. sativa seeds and oil have been used …

Oleoresin of Nigella sativa L.(Black cumin) was obtained from the seeds using hexane
extraction at room temperature. The oleoresin was emulsified in an aqueous solution …

Doxorubicin (DOX) is used as an anticancer drug despite its many side effects.
Thymoquinone (THQ) is a plant-derived substance that exhibits antioxidant and anti …

N-Acetyl-p-Aminophenol (APAP), also known as acetaminophen, is the most commonly
used over-the counter analgesic and antipyretic medication. However, its overdose leads to …

Background: Kidneys as vital organs remove waste material from blood. Additionally, they
may also have a role in the electrolyte balance, regulation of blood pressure, and red blood …

Background It is well established that renin-angiotensin system (RAS) play a central role in
pathophysiology of renal damage following unilateral ureteral obstruction (UUO). The …

Thymoquinone is the main active monomer extracted from black cumin and has anti‑
inflammatory, antioxidant and anti‑apoptotic functions. However, the protective effects of …

Background and objectives N-(4-hydroxyphenyl) acetamide (NHPA) is the most commonly
used analgesic and antipyretic agent worldwide; however, it remains the leading cause of …

Objectives Acetaminophen (APAP)-induced nephrotoxicity is detrimental consequence for
which there has not been a standardized therapeutic regimen. Although, N-acetylcysteine …