Functional assays to evaluate antibody-mediated responses against Shigella: a review
Shigella is a major global pathogen and the etiological agent of shigellosis, a diarrheal
disease that primarily affects low-and middle-income countries. Shigellosis is characterized …
disease that primarily affects low-and middle-income countries. Shigellosis is characterized …
A broadly immunogenic polyvalent Shigella multiepitope fusion antigen protein protects against Shigella sonnei and Shigella flexneri lethal pulmonary challenges …
S Li, S Anvari, G Ptacek, I Upadhyay… - Infection and …, 2023 - Am Soc Microbiol
There are no licensed vaccines for Shigella, a leading cause of children's diarrhea and a
common etiology of travelers' diarrhea. To develop a cross-protective Shigella vaccine, in …
common etiology of travelers' diarrhea. To develop a cross-protective Shigella vaccine, in …
Polyvalent protein adhesin MEFA-II induces functional antibodies against enterotoxigenic Escherichia coli (ETEC) adhesins CS7, CS12, CS14, CS17, and CS21 and …
I Upadhyay, SMD Parvej, S Li, KL Lauder… - Applied and …, 2023 - Am Soc Microbiol
There are no licensed vaccines for enterotoxigenic Escherichia coli (ETEC), a common
cause of children's diarrhea and travelers' diarrhea. ETEC strains producing enterotoxins …
cause of children's diarrhea and travelers' diarrhea. ETEC strains producing enterotoxins …
Mapping the functional B-cell epitopes of Shigella invasion plasmid antigen D (IpaD)
S Li, W Zhang - Applied and Environmental Microbiology, 2024 - journals.asm.org
Shigella bacteria utilize the type III secretion system (T3SS) to invade host cells and
establish local infection. Invasion plasmid antigen D (IpaD), a component of Shigella T3SS …
establish local infection. Invasion plasmid antigen D (IpaD), a component of Shigella T3SS …
Induction of Viable but Non-culturable (VBNC) State in Shigella flexneri Under Osmotic and Nutritional Stresses at Low Temperature
AN Baghi, MR Ardakani… - Jundishapur Journal of …, 2024 - search.proquest.com
1. Background The viable but non-culturable (VBNC) state is a microbial survival strategy in
response to unfavorable physicochemical conditions, characterized by the loss of …
response to unfavorable physicochemical conditions, characterized by the loss of …
Confirmation of candidates identified by reverse vaccinology in animal models or other immunogenicity assays
A de Oliveira Matos, PH dos Santos Dantas… - Reverse …, 2024 - Elsevier
The use of reverse vaccinology (RV) has drastically improved the development of vaccines.
The combination of different in silico tools had a great impact on reducing the time and …
The combination of different in silico tools had a great impact on reducing the time and …