Biological insights from the premonitory symptoms of migraine

N Karsan, PJ Goadsby - Nature Reviews Neurology, 2018 - nature.com
Migraine is a common neurological disorder with a diverse clinical phenotype that
comprises more than just head pain. Premonitory (prodromal) symptoms can start hours to …

Hypothalamic regulation of headache and migraine

A May, R Burstein - Cephalalgia, 2019 - journals.sagepub.com
Background The clinical picture, but also neuroimaging findings, suggested the brainstem
and midbrain structures as possible driving or generating structures in migraine. Findings …

The migraine postdrome: an electronic diary study

NJ Giffin, RB Lipton, SD Silberstein, J Olesen… - Neurology, 2016 - AAN Enterprises
Objective: To report migraine postdrome symptoms in patients who report nonheadache
symptoms as part of their attacks. Methods: A prospective daily electronic diary study was …

Hypothalamus as a mediator of chronic migraine: evidence from high-resolution fMRI

LH Schulte, A Allers, A May - Neurology, 2017 - AAN Enterprises
Objective: To identify pathophysiologic mechanisms of migraine chronification using a
recently standardized protocol for high-resolution brainstem imaging of trigeminal …

Longitudinal neuroimaging over 30 days: temporal characteristics of migraine

LH Schulte, J Mehnert, A May - Annals of neurology, 2020 - Wiley Online Library
Objective Although migraine is defined by the headache and headache‐associated
symptoms, the true beginning of a migraine attack lies in the premonitory phase. To …

The evolution of a migraine attack–a review of recent evidence

A Charles - Headache: The Journal of Head and Face Pain, 2013 - Wiley Online Library
A migraine attack is an extraordinarily complex brain event that takes place over hours to
days. This review focuses on recent human studies that shed light on the evolution of a …

The migraineur's brain networks: Continuous resting state fMRI over 30 days

LH Schulte, MM Menz, J Haaker, A May - Cephalalgia, 2020 - journals.sagepub.com
Objective The aim of the current study was to identify typical alterations in resting state
connectivity within different stages of the migraine cycle and to thus explore task-free …

Premonitory symptoms in migraine: a cross-sectional study in 2714 persons

K Laurell, V Artto, L Bendtsen, K Hagen… - …, 2016 - journals.sagepub.com
Aim To describe the frequency and number of premonitory symptoms (PS) in migraine, the
co-occurrence of different PS, and their association with migraine-related factors. Methods In …

Pathophysiological mechanisms in migraine and the identification of new therapeutic targets

KA Haanes, L Edvinsson - CNS drugs, 2019 - Springer
Migraine is a strongly disabling disease characterized by a unilateral throbbing headache
lasting for up to 72 h for each individual attack. There have been many theories on the …

Trigger factors and premonitory features of migraine attacks: summary of studies

JM Pavlovic, DC Buse, CM Sollars… - … : The Journal of …, 2014 - Wiley Online Library
Objective In this second of a 2‐part series, we review the available literature on trigger
factors and premonitory features in migraine. Background In the absence of biological …