Active pharmaceutical ingredients (APIs) may exist in various solid forms, which can lead to
differences in the intermolecular interactions, affecting the internal energy and enthalpy, and …

In recent years many efforts have been devoted to the screening and the study of new solid-
state forms of old active pharmaceutical ingredients (APIs) with salification or co …

This overview highlights the emergent area of mechanochemical reactions for making active
pharmaceutical ingredients (APIs), and covers the latest advances in the recently …

Mechanochemistry is an effective method for the preparation of multicomponent crystal
systems. In the present work, we propose an alternative to the established liquid‐assisted …

Cocrystals have gained much interest in recent years owing to their potential to improve the
physicochemical properties of the parent compounds. It was once thought that cocrystals …

Within the pharmaceutical industry, and elsewhere, the screening for new solid forms is a
mandatory exercise for both existing and new chemical entities. This contribution focuses on …

Design and synthesis of pharmaceutical cocrystals have received great interest in recent
years. Cocrystallization of drug substances offers a tremendous opportunity for the …

Curcumin (CUR) is the prime curcuminoid in the Indian dietary spice turmeric, Curcuma
longa, a plant of the Zingiberaceae family. CUR has promising and diverse therapeutic …

Cocrystallization is currently having a tremendous impact on pharmaceuticals [1] and
energetic materials (energetics)[2] and is poised to make a significant mark on other fields …

Cocrystals are crystalline single phase materials composed of two or more different
molecular and/or ionic compounds generally in a stoichiometric ratio which are neither …