Long known as digestive organelles, lysosomes have now emerged as multifaceted centers
responsible for degradation, nutrient sensing, and immunity. Growing evidence also …

Peripheral artery disease (PAD) affects 200 million individuals worldwide. In the United
States, certain demographic groups experience a disproportionately higher prevalence and …

AMPK activated protein kinase (AMPK), a master regulator of energy homeostasis, is
activated in response to an energy shortage imposed by physical activity and caloric …

Introduction Lumbar spinal stenosis (LSS) is a common spinal disease of aging with a
growing patient population, paralleling population growth. Minimally invasive treatments are …

Objectives Supervised exercise programmes (SEPs) are a vital treatment for people with
intermittent claudication, leading improvements in walking distance and quality of life and …

Peripheral artery disease (PAD) is caused by atherosclerosis in the lower extremities, which
leads to a spectrum of life-altering symptomatology, including claudication, ischemic rest …

Ischemic vascular disease is a major healthcare problem. The keys to treatment lie in
vascular regeneration and restoration of perfusion. However, current treatments cannot …

El pie diabético es una complicación crónica de la diabetes que consiste en lesiones en los
tejidos profundos de las extremidades inferiores asociadas con trastornos neurológicos y …

Background Walking limitation in patients with peripheral arterial disease (PAD) and
intermittent claudication (IC) contributes to poorer disease outcomes. Identifying and …

Background: Broadly available digital and mobile health applications (also known as
mHealth) have recently gained increasing attention by the vascular community, but very little …