Obstructive sleep apnea and inflammation: proof of concept based on two illustrative cytokines

L Kheirandish-Gozal, D Gozal - International journal of molecular …, 2019 - mdpi.com
Obstructive sleep apnea syndrome (OSAS) is a markedly prevalent condition across the
lifespan, particularly in overweight and obese individuals, which has been associated with …

Light and cognition: roles for circadian rhythms, sleep, and arousal

AS Fisk, SKE Tam, LA Brown, VV Vyazovskiy… - Frontiers in …, 2018 - frontiersin.org
Light exerts a wide range of effects on mammalian physiology and behavior. As well as
synchronizing circadian rhythms to the external environment, light has been shown to …

Chronic sleep disruption alters gut microbiota, induces systemic and adipose tissue inflammation and insulin resistance in mice

VA Poroyko, A Carreras, A Khalyfa, AA Khalyfa… - Scientific reports, 2016 - nature.com
Chronic sleep fragmentation (SF) commonly occurs in human populations, and although it
does not involve circadian shifts or sleep deprivation, it markedly alters feeding behaviors …

[HTML][HTML] Acute sleep deprivation exacerbates systemic inflammation and psychiatry disorders through gut microbiota dysbiosis and disruption of circadian rhythms

DF Yang, WC Huang, CW Wu, CY Huang… - Microbiological …, 2023 - Elsevier
Acute sleep deprivation (ASD) is often observed in shift workers and characterized by
drowsiness and unrelenting exhaustion. The physiological and psychological effects of ASD …

Regulation of the blood–brain barrier by circadian rhythms and sleep

VA Cuddapah, SL Zhang, A Sehgal - Trends in neurosciences, 2019 - cell.com
The blood–brain barrier (BBB) is an evolutionarily conserved, structural, and functional
separation between circulating blood and the central nervous system (CNS). By controlling …

Inhibiting the microglia activation improves the spatial memory and adult neurogenesis in rat hippocampus during 48 h of sleep deprivation

M Wadhwa, A Prabhakar, K Ray, K Roy… - Journal of …, 2017 - Springer
Background Sleep deprivation (SD) leads to cognitive impairment. Neuroinflammation could
be a significant contributing factor in the same. An increase in regional brain pro …

“Heads Up” for Creatine Supplementation and its Potential Applications for Brain Health and Function

DG Candow, SC Forbes, SM Ostojic, K Prokopidis… - Sports Medicine, 2023 - Springer
There is emerging interest regarding the potential beneficial effects of creatine
supplementation on indices of brain health and function. Creatine supplementation can …

Fragmented sleep accelerates tumor growth and progression through recruitment of tumor-associated macrophages and TLR4 signaling

F Hakim, Y Wang, SXL Zhang, J Zheng, ES Yolcu… - Cancer research, 2014 - AACR
Sleep fragmentation (SF) is a highly prevalent condition and a hallmark of sleep apnea, a
condition that has been associated with increased cancer incidence and mortality. In this …

Blood‐brain barrier disruption induced by chronic sleep loss: low‐grade inflammation may be the link

G Hurtado-Alvarado… - Journal of …, 2016 - Wiley Online Library
Sleep is a vital phenomenon related to immunomodulation at the central and peripheral
level. Sleep deficient in duration and/or quality is a common problem in the modern society …

Biological plausibility linking sleep apnoea and metabolic dysfunction

A Gileles-Hillel, L Kheirandish-Gozal… - Nature Reviews …, 2016 - nature.com
Obstructive sleep apnoea (OSA) is a very common disorder that affects 10–25% of the
general population. In the past two decades, OSA has emerged as a cardiometabolic risk …