Possible mechanisms of oxidative stress-induced skin cellular senescence, inflammation, and cancer and the therapeutic potential of plant polyphenols

HM Liu, MY Cheng, MH Xun, ZW Zhao… - International Journal of …, 2023 - mdpi.com
As the greatest defense organ of the body, the skin is exposed to endogenous and external
stressors that produce reactive oxygen species (ROS). When the antioxidant system of the …

Silver nanoparticles in aquatic environments: Physiochemical behavior and antimicrobial mechanisms

C Zhang, Z Hu, B Deng - Water research, 2016 - Elsevier
Nanosilver (silver nanoparticles or AgNPs) has unique physiochemical properties and
strong antimicrobial activities. This paper provides a comprehensive review of the …

ROS-generating amine-functionalized magnetic nanoparticles coupled with carboxymethyl chitosan for pH-responsive release of doxorubicin

SR Obireddy, WF Lai - International Journal of Nanomedicine, 2022 - Taylor & Francis
Purpose Magnetic nanoparticles have been used in diverse pharmaceutical applications
because they can potentially be used to target specific sites. In the present work, a new type …

Redox interactions and genotoxicity of metal-based nanoparticles: A comprehensive review

K Mortezaee, M Najafi, H Samadian, H Barabadi… - Chemico-biological …, 2019 - Elsevier
Nanotechnology is a growing science that may provide several new applications for
medicine, food preservation, diagnostic technologies, and sanitation. Despite its beneficial …

Reduced graphene oxide–silver nanoparticle nanocomposite: a potential anticancer nanotherapy

S Gurunathan, JW Han, JH Park, E Kim… - International journal …, 2015 - Taylor & Francis
Background Graphene and graphene-based nanocomposites are used in various research
areas including sensing, energy storage, and catalysis. The mechanical, thermal, electrical …

[HTML][HTML] Support for the safe use of zinc oxide nanoparticle sunscreens: lack of skin penetration or cellular toxicity after repeated application in volunteers

YH Mohammed, A Holmes, IN Haridass… - Journal of Investigative …, 2019 - Elsevier
Zinc oxide is a widely used broad-spectrum sunscreen, but concerns have been raised
about the safety of its nanoparticle (NP) form. We studied the safety of repeated application …

Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K …

C Guo, M Yang, LI Jing, J Wang, Y Yu, Y Li… - International journal …, 2016 - Taylor & Francis
Environmental exposure to silica nanoparticles (SiNPs) is inevitable due to their widespread
application in industrial, commercial, and biomedical fields. In recent years, most …

Nickel carcinogenesis mechanism: DNA damage

H Guo, H Liu, H Wu, H Cui, J Fang, Z Zuo… - International journal of …, 2019 - mdpi.com
Nickel (Ni) is known to be a major carcinogenic heavy metal. Occupational and
environmental exposure to Ni has been implicated in human lung and nasal cancers …

Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling

C Guo, Y Xia, P Niu, L Jiang, J Duan, Y Yu… - International journal …, 2015 - Taylor & Francis
Despite the widespread application of silica nanoparticles (SiNPs) in industrial, commercial,
and biomedical fields, their response to human cells has not been fully elucidated. Overall …

Iron oxide nanoparticles induce oxidative stress, DNA damage, and caspase activation in the human breast cancer cell line

S Alarifi, D Ali, S Alkahtani, MS Alhader - Biological trace element …, 2014 - Springer
Broad applications of iron oxide nanoparticles require an improved understanding of their
potential effects on human health. In the present study, we explored the underlying …