Pulmonary drug delivery is the focus of much research and development because of its
great potential to produce maximum therapeutic benefit. Among the available options the dry …

Introduction: The effectiveness of drug delivery to the lungs is inextricably linked to the
fundamental interactions that occur between particles and flow in the extrathoracic airway …

Understanding and controlling powder de-agglomeration is of great importance in the
development of dry powder inhaler (DPI) products. Dry dispersion laser diffraction measures …

Large porous particles are becoming increasingly popular as carriers for pulmonary drug
delivery with both local and systemic applications. These particles have high geometric …

Purpose The objective of this study was to explore the performance of a high efficiency dry
powder inhaler (DPI) intended for excipient enhanced growth (EEG) aerosol delivery based …

Abstract Development of carrier-based dry powder inhalation formulations follows till date
empirical approaches. This is mainly underlain by numerousness of interplaying …

The potential of fine excipient materials to improve the performance of carrier-based dry
powder inhalation mixtures is well acknowledged. The mechanisms underlying this potential …

The purpose of the present study was to develop guidance toward rational choice of
blenders and processing conditions to make robust and high performing adhesive mixtures …

Purpose The purpose of the study was to understand the role of particle size and shape
changes in modifying agglomerate strength distribution and de-agglomeration of cohesive …

Purpose The purpose was to calculate distributions of powder strength of a cohesive bed to
explain the de-agglomeration of lactose. Methods De-agglomeration profiles of Lactohale …