Identification, discrimination and heterogeneity of fibroblasts

U Lendahl, L Muhl, C Betsholtz - Nature communications, 2022 - nature.com
Fibroblasts, the principal cell type of connective tissue, secrete extracellular matrix
components during tissue development, homeostasis, repair and disease. Despite this …

[HTML][HTML] Prevention strategies of postoperative adhesion in soft tissues by applying biomaterials: Based on the mechanisms of occurrence and development of …

J Liao, X Li, Y Fan - Bioactive Materials, 2023 - Elsevier
Postoperative adhesion (POA) widely occurs in soft tissues and usually leads to chronic
pain, dysfunction of adjacent organs and some acute complications, seriously reducing …

Aged skeletal stem cells generate an inflammatory degenerative niche

TH Ambrosi, O Marecic, A McArdle, R Sinha, GS Gulati… - Nature, 2021 - nature.com
Loss of skeletal integrity during ageing and disease is associated with an imbalance in the
opposing actions of osteoblasts and osteoclasts. Here we show that intrinsic ageing of …

Injectable immunomodulation-based porous chitosan microspheres/HPCH hydrogel composites as a controlled drug delivery system for osteochondral regeneration

X Ji, H Shao, X Li, MW Ullah, G Luo, Z Xu, L Ma, X He… - Biomaterials, 2022 - Elsevier
The inappropriate regenerated fibrous cartilage and subchondral bone of the injured
chondral defect ultimately cause degeneration of the regenerated cartilage, which …

Peritoneum‐inspired Janus porous hydrogel with anti‐deformation, anti‐adhesion, and pro‐healing characteristics for abdominal wall defect treatment

W Liang, W He, R Huang, Y Tang, S Li… - Advanced …, 2022 - Wiley Online Library
Implantable meshes used in tension‐free repair operations facilitate treatment of internal soft‐
tissue defects. However, clinical meshes fail to achieve anti‐deformation, anti‐adhesion …

In-situ growth of robust superlubricated nano-skin on electrospun nanofibers for post-operative adhesion prevention

Y Wang, Y Xu, W Zhai, Z Zhang, Y Liu, S Cheng… - Nature …, 2022 - nature.com
It is a great challenge to achieve robustly bonded, fully covered, and nanoscaled coating on
the surface of electrospun nanofibers. Herein, we develop a controllable, facile, and …

Multifunctional microgel-based cream hydrogels for postoperative abdominal adhesion prevention

B Liu, Y Kong, OA Alimi, MA Kuss, H Tu, W Hu… - ACS …, 2023 - ACS Publications
Postoperative abdominal adhesions are a common problem after surgery and can produce
serious complications. Current antiadhesive strategies focus mostly on physical barriers and …

Establishments and evaluations of post‐operative adhesion animal models

Y Wang, W Zhai, L Yang, S Cheng… - Advanced …, 2023 - Wiley Online Library
After abdominopelvic surgery, there are 90–93% of patients who develop postoperative
adhesions. Post‐operative adhesions can occur after various surgical procedures, which not …

Schwann cell precursors represent a neural crest‐like state with biased multipotency

ME Kastriti, L Faure, D Von Ahsen… - The EMBO …, 2022 - embopress.org
Schwann cell precursors (SCPs) are nerve‐associated progenitors that can generate
myelinating and non‐myelinating Schwann cells but also are multipotent like the neural …

Post-operative adhesions: a comprehensive review of mechanisms

A Fatehi Hassanabad, AN Zarzycki, K Jeon, JF Deniset… - Biomedicines, 2021 - mdpi.com
Post-surgical adhesions are common in almost all surgical areas and are associated with
significant rates of morbidity, mortality, and increased healthcare costs, especially when a …