ArcAB, also known as the Arc system, is a member of the two-component system family of
bacterial transcriptional regulators and is composed of sensor kinase ArcB and response …

The Host-microbiome interactions that exist inside the gut microbiota operate in a synergistic
and abnormal manner. Additionally, the normal homeostasis and functioning of gut …

There is an urgent need for strategies to discover secondary drugs to prevent or disrupt
antimicrobial resistance (AMR), which is causing> 700,000 deaths annually. Here, we …

The increasing prevalence of antimicrobial resistance and the limited availability of new
antimicrobial agents have created an urgent need for new approaches to combat these …

Despite mounting evidence that in clonal bacterial populations, phenotypic variability
originates from stochasticity in gene expression, little is known about noise-shaping …

Antimicrobial resistance (AMR) in bacteria is an important global health problem affecting
humans, animals, and the environment. AMR is considered as one of the major components …

Despite the urgent need for new antibiotics, very few innovative antibiotics have recently
entered clinics or clinical trials. To provide a constant supply of new drug candidates …

Efflux pumps are well known to be an important mechanism for removing noxious
substances such as antibiotics from bacteria. Given that many antibiotics function by …

Genetic interaction (GI) analysis is a powerful genetic strategy that analyzes the fitness and
phenotypes of single-and double-gene mutant cells in order to dissect the epistatic …

The incidence of antibiotics and transcriptional regulation of ARGs in isolated bacteria from
wastewater needs to be explored. By HPLC, in samples of untreated wastewater, ampicillin …