A review of cancer immunotherapy toxicity

LB Kennedy, AKS Salama - CA: a cancer journal for clinicians, 2020 - Wiley Online Library
Cancer immunotherapies, including checkpoint inhibitors and adoptive cell therapy,
manipulate the immune system to recognize and attack cancer cells. These therapies have …

Neurological toxicities associated with immune-checkpoint inhibitors

M Touat, D Talmasov, D Ricard… - Current opinion in …, 2017 - journals.lww.com
ICI-associated irAEs constitute a new group of neurologic complications of systemic
anticancer therapies. Although potentially severe, these rare neurologic toxicities are often …

Immune checkpoint inhibitor-related myositis and myocarditis in patients with cancer

M Touat, T Maisonobe, S Knauss, O Ben Hadj Salem… - Neurology, 2018 - AAN Enterprises
Objective To report the clinicopathologic features and outcome of myositis in patients treated
with immune checkpoint inhibitors (ICIs)(irMyositis). Methods We retrospectively analyzed …

EULAR points to consider for the diagnosis and management of rheumatic immune-related adverse events due to cancer immunotherapy with checkpoint inhibitors

M Kostine, A Finckh, CO Bingham, K Visser… - Annals of the …, 2021 - ard.bmj.com
Background Rheumatic and musculoskeletal immune-related adverse events (irAEs) are
observed in about 10% of patients with cancer receiving checkpoint inhibitors (CPIs). Given …

[HTML][HTML] Myositis and neuromuscular side-effects induced by immune checkpoint inhibitors

A Moreira, C Loquai, C Pföhler, KC Kähler… - European Journal of …, 2019 - Elsevier
Aim To characterise clinical presentation, laboratory and histopathologic characteristics and
assess the treatment and outcome of neuromuscular side-effects of checkpoint therapy …

Neurological complications associated with anti–programmed death 1 (PD-1) antibodies

JC Kao, B Liao, SN Markovic, CJ Klein… - JAMA …, 2017 - jamanetwork.com
Importance Neurological complications are an increasingly recognized consequence of the
use of anti–programmed death 1 (PD-1) antibodies in the treatment of solid-organ tumors …

Neurological immune related adverse events associated with nivolumab, ipilimumab, and pembrolizumab therapy—review of the literature and future outlook

N Möhn, G Beutel, R Gutzmer, P Ivanyi… - Journal of Clinical …, 2019 - mdpi.com
Immune checkpoint inhibitor (ICI) therapy has revolutionized the management of various
cancers with previously poor prognosis. Despite its great efficacy, the therapy is associated …

Neuromuscular adverse events associated with anti-PD-1 monoclonal antibodies: systematic review

A Johansen, SJ Christensen, D Scheie, JLS Højgaard… - Neurology, 2019 - AAN Enterprises
Neuromuscular adverse events following cancer treatment with anti-programmed cell death
protein 1 (PD-1) monoclonal antibodies are relatively rare, yet potentially fatal. We …

PD-1 inhibitor-associated myopathies: emerging immune-mediated myopathies

T Liewluck, JC Kao, ML Mauermann - Journal of Immunotherapy, 2018 - journals.lww.com
Abstract Programmed death-1 (PD-1) inhibitors are increasingly used in cancer
immunotherapy. Various immune-related adverse events are reported, including infrequent …

Neuromuscular complications of programmed cell death-1 (PD-1) inhibitors

JC Kao, A Brickshawana, T Liewluck - Current Neurology and …, 2018 - Springer
Abstract Purpose of Review In recent years, immune checkpoint inhibitors have been
increasingly used in patients with metastatic cancers with favorable oncological outcomes; …