Microglia are mononuclear phagocytes of mesodermal origin that migrate to the central
nervous system (CNS) during the early stages of embryonic development. After colonizing …

Microglia are so versatile that they not only provide immune surveillance for central nervous
system, but participate in neural circuitry development, brain blood vessels formation, blood …

The hypothalamus (“hypo” meaning below, and “thalamus” meaning bed) consists of
regulatory circuits that support basic life functions that ensure survival. Sitting at the interface …

Neurodevelopmental disorders arise due to various risk factors that can perturb different
stages of brain development, and a combinatorial impact of these risk factors programs the …

Activation of the maternal immune system during gestation has been associated with an
increased risk for neurodevelopmental disorders in the offspring, particularly schizophrenia …

The biogenic amine, histamine, has been shown to critically modulate inflammatory
processes as well as the properties of neurons and synapses in the brain, and is also …

Background Microglia are tissue resident macrophages with a wide range of critically
important functions in central nervous system development and homeostasis. Method In this …

An interdisciplinary fetal-neonatal neurology (FNN) program over the first 1,000 days
teaches perspectives of the neural exposome that are applicable across the life span. This …

Inflammation during prenatal development can be detrimental to neurodevelopmental
processes, increasing the risk of neuropsychiatric disorders. Prenatal exposure to maternal …

Neural stem and precursor cells (NPCs) build and regenerate the central nervous system
(CNS) by maintaining their pool (self-renewal) and differentiating into neurons, astrocytes …