DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation

Q Zhang, P Feng, XH Zhu, SQ Zhou, ML Ye… - Cell Death & …, 2023 - nature.com
Emerging evidence indicates that DNA methylation plays an important role in the initiation
and progression of nasopharyngeal carcinoma (NPC). DNAJA4 is hypermethylated in NPC …

[HTML][HTML] PSMD11 promotes the proliferation of hepatocellular carcinoma by regulating the ubiquitination degradation of CDK4

L Sun, Z Liu, Z Wu, Z Wu, B Qiu, S Liu, J Hu, X Yin - Cellular Signalling, 2024 - Elsevier
Background The 26S proteasome non-ATPase regulatory subunit 11 is a multiprotein
complex involved in the ATP-dependent degradation of ubiquitinated proteins, and PSMD11 …

Prognostic implication and immunological role of PSMD2 in lung adenocarcinoma

H Zhao, G Lu - Frontiers in Genetics, 2022 - frontiersin.org
Background: Although previous studies reported that 26S proteasome non-ATPase
regulatory subunit 2 (PSMD2) is involved in many human cancers. However, its clinical …

PSMD12 interacts with CDKN3 and facilitates pancreatic cancer progression

J Ma, W Zhou, Y Yuan, B Wang, X Meng - Cancer gene therapy, 2023 - nature.com
Proteasome 26S subunit, non-ATPase 12 (PSMD12) genes have been implicated in several
types of malignancies but the role of PSMD12 in pancreatic cancer (PC) remains elusive …

The clinicopathological and prognostic significance of PSMD14 in cancers based on bioinformatics and meta-analysis

SY Dong, S Ding, Z Meng, B Zou - Future Science OA, 2024 - Taylor & Francis
Aim: To evaluate the clinic-pathological features and prognostic value regarding PSMD14 in
cancers. Materials & methods: Literature was gathered from public databases until 22 June …

Metabolomic Biomarkers for Prognosis in Non-Muscle Invasive Bladder Cancer: A Comprehensive Systematic Review and Meta-Analysis

V Singh, MK Singh, A Kumar, DK Sahu, M Jain… - Indian Journal of Clinical …, 2024 - Springer
The prognostic biomarkers, or metabolites, have gained relevance due to their significance
in predicting clinical and therapeutic outcomes and guiding informed therapy options. This …

An integrative analysis reveals the prognostic value and potential functions of PSMD11 in hepatocellular carcinoma

C Zhang, T Xu, K Ji, S Cao, Y Cao, J Ai… - Molecular …, 2023 - Wiley Online Library
The global burden of hepatocellular carcinoma (HCC) as a preeminent etiology of cancer‐
related mortalities sheds light on the imperative necessity for a more profound …

19S Proteasome subunits as oncogenes and prognostic biomarkers in FLT3-mutated acute myeloid leukemia (AML)

JJ Lara, AE Bencomo-Alvarez, MA Gonzalez… - International Journal of …, 2022 - mdpi.com
26S proteasome non-ATPase subunits 1 (PSMD1) and 3 (PSMD3) were recently identified
as prognostic biomarkers and potential therapeutic targets in chronic myeloid leukemia …

PSMD3-ILF3 signaling cascade drives lung cancer cell proliferation and migration

J Zhang, Q Ma, Q Yu, F Xiao, Z Zhang, H Feng, C Liang - Biology Direct, 2023 - Springer
Background Proteasome 26S subunit, non-ATPase 3 (PSMD3) has been reported to
participate in various human cancers. Nevertheless, the function of PSMD3 in lung cancer …

Biomarker discovery with quantum neural networks: a case-study in CTLA4-activation pathways

PN Nguyen - BMC bioinformatics, 2024 - Springer
Background Biomarker discovery is a challenging task due to the massive search space.
Quantum computing and quantum Artificial Intelligence (quantum AI) can be used to address …