Exercise intolerance is the cardinal symptom of heart failure (HF) and is of crucial relevance,
because it is associated with a poor quality of life and increased mortality. While impaired …

Heart failure is characterized by pathologic hemodynamic derangements, including elevated
cardiac filling pressures (“backward” failure), which may or may not coexist with reduced …

Compared with traditional exercise tests, cardiopulmonary exercise testing (CPET) provides
a thorough assessment of exercise integrative physiology involving the pulmonary …

Heart failure (HF) remains a major cause of mortality, morbidity, and poor quality of life. It is
an area of active research. This article is aimed to give an update on recent advances in all …

Patients with heart failure with preserved ejection fraction (HFpEF) universally complain of
exercise intolerance and dyspnoea as key clinical correlates. Cardiac as well as …

Aims Increases in extravascular lung water (EVLW) during exercise contribute to symptoms,
morbidity, and mortality in patients with heart failure and preserved ejection fraction …

Aims Pulmonary hypertension (PH) and pulmonary vascular disease (PVD) are common
and associated with adverse outcomes in left heart disease (LHD). This study sought to …

Aims Increases in left ventricular filling pressure are a fundamental haemodynamic
abnormality in heart failure with preserved ejection fraction (HFpEF). However, very little is …

Research about heart failure (HF) has made major progress in the last years. We give here
an update on the most recent findings. Landmark trials have established new treatments for …

Cardiopulmonary exercise testing (CPET) is a frequently used tool in the differential
diagnosis of dyspnoea. Ventilatory inefficiency, defined as high minute ventilation (V′ E) …