We herein present an overview of the upcoming 5th edition of the World Health Organization
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …

Pediatric tumors are uncommon, yet are the leading cause of cancer-related death in
childhood. Tumor types, molecular characteristics, and pathogenesis are unique, often …

The classification of myeloid neoplasms and acute leukemias was last updated in 2016
within a collaboration between the World Health Organization (WHO), the Society for …

Acute lymphoblastic leukemia (ALL) is the second most common acute leukemia in adults,
with an incidence of over 6500 cases per year in the United States alone. The hallmark of …

Importance An increased risk of lymphoma has been reported among patients receiving
thiopurines for inflammatory bowel disease (IBD). The risk of lymphoma associated with anti …

Our knowledge about the genetics of myelodysplastic syndromes (MDS) and related
myeloid disorders has been dramatically improved during the past decade, in which …

Acute myeloid leukemia (AML) is the most common form of acute leukemia among adults
and accounts for the largest number of annual deaths due to leukemias in the United States …

To elucidate differential roles of mutations in myelodysplastic syndromes (MDS), we
investigated clonal dynamics using whole-exome and/or targeted sequencing of 699 …

Background Rituximab plus chemotherapy, most often CHOP (cyclophosphamide,
doxorubicin, vincristine, and prednisone), is the first-line standard of care for patients with …

The myelodysplastic syndromes (MDS) comprise a heterogenous group of myeloid
disorders with a highly variable disease course. Diagnostic criteria to better stratify patients …