Targeting matrix metalloproteases in diabetic wound healing

J Chen, S Qin, S Liu, K Zhong, Y Jing, X Wu… - Frontiers in …, 2023 - frontiersin.org
Chronic inflammation participates in the progression of multiple chronic diseases, including
obesity, diabetes mellitus (DM), and DM related complications. Diabetic ulcer, characterized …

Unravelling the potential of insects for medicinal purposes–a comprehensive review

SA Siddiqui, C Li, OF Aidoo, I Fernando, MA Haddad… - Heliyon, 2023 - cell.com
Entomotherapy, the use of insects for medicinal purposes, has been practised for centuries
in many countries around the world. More than 2100 edible insect species are eaten by …

The antimicrobial peptide human β-defensin-3 accelerates wound healing by promoting angiogenesis, cell migration, and proliferation through the FGFR/JAK2/STAT3 …

M Takahashi, Y Umehara, H Yue… - Frontiers in …, 2021 - frontiersin.org
In addition to its antimicrobial activity, the skin-derived antimicrobial peptide human β-
defensin-3 (hBD-3) promotes keratinocyte proliferation and migration to initiate the wound …

Stem cell-based therapy for diabetic foot ulcers

Q Yu, G Qiao, M Wang, L Yu, Y Sun, H Shi… - Frontiers in Cell and …, 2022 - frontiersin.org
Diabetic foot ulcer has become a worldwide clinical medical challenge as traditional
treatments are not effective enough to reduce the amputation rate. Therefore, it is of great …

Therapeutic potential of luteolin on impaired wound healing in streptozotocin-induced rats

LY Chen, HL Cheng, YH Kuan, TJ Liang, YY Chao… - Biomedicines, 2021 - mdpi.com
Long-term hyperglycemia may lead to diabetic microvascular and macrovascular
complications that can affect the peripheral vascular system, particularly in wound healing …

Topical metformin accelerates wound healing by promoting collagen synthesis and inhibiting apoptosis in a diabetic wound model

FK Tombulturk, T Soydas… - International wound …, 2024 - Wiley Online Library
The wound healing process, which is a pathophysiological process that includes various
phases, is interrupted in diabetes due to hyperglycemia, and since deterioration occurs in …

Highly porous and superabsorbent biomaterial made of marine-derived polysaccharides and ascorbic acid as an optimal dressing for exuding wound management

V Vivcharenko, M Wojcik, K Palka, A Przekora - Materials, 2021 - mdpi.com
There are many modern wound dressings that have promising properties for repairing skin
damage. However, due to various types of wounds and the problems they cause, there is …

The effect of Lucilia sericata larval excretion/secretion (ES) products on cellular responses in wound healing

U Gazi, A Taylan‐Ozkan… - Medical and veterinary …, 2021 - Wiley Online Library
Chronic wounds are still regarded as a serious public health concern, which are on the
increase mainly due to the changes in life styles and aging of the human population. There …

Insights into the immunomodulatory regulation of matrix metalloproteinase at the maternal-fetal interface during early pregnancy and pregnancy-related diseases

M Jing, X Chen, H Qiu, W He, Y Zhou, D Li… - Frontiers in …, 2023 - frontiersin.org
Trophoblast immune cell interactions are central events in the immune microenvironment at
the maternal-fetal interface. Their abnormalities are potential causes of various pregnancy …

Evaluating leishmanicidal effects of Lucilia sericata products in combination with Apis mellifera honey using an in vitro model

J Sherafati, MS Dayer, F Ghaffarifar, K Akbarzadeh… - Plos one, 2023 - journals.plos.org
Leishmaniasis is a zoonotic disease caused by an intracellular parasite from the genus
Leishmania. Lack of safe and effective drugs has increasingly promoted researches into …