The evolution of RNA structural probing methods: from gels to next‐generation sequencing

E Mailler, JC Paillart, R Marquet… - Wiley …, 2019 - Wiley Online Library
RNA molecules are important players in all domains of life and the study of the relationship
between their multiple flexible states and the associated biological roles has increased in …

New insights from cluster analysis methods for RNA secondary structure prediction

E Rogers, C Heitsch - Wiley Interdisciplinary Reviews: RNA, 2016 - Wiley Online Library
A widening gap exists between the best practices for RNA secondary structure prediction
developed by computational researchers and the methods used in practice by …

INTERPIN: A repository for intrinsic transcription termination hairpins in bacteria

S Gupta, N Padmashali, D Pal - Biochimie, 2023 - Elsevier
The large-scale detection of putative intrinsic transcription terminators is limited to only a few
bacteria currently. We discovered a group of hairpins, called cluster hairpins, present within …

Knotify: An efficient parallel platform for RNA pseudoknot prediction using syntactic pattern recognition

C Andrikos, E Makris, A Kolaitis, G Rassias… - Methods and …, 2022 - mdpi.com
Obtaining valuable clues for noncoding RNA (ribonucleic acid) subsequences remains a
significant challenge, acknowledging that most of the human genome transcribes into …

Knotify+: toward the prediction of RNA H-type pseudoknots, including bulges and internal loops

E Makris, A Kolaitis, C Andrikos, V Moulos, P Tsanakas… - Biomolecules, 2023 - mdpi.com
The accurate “base pairing” in RNA molecules, which leads to the prediction of RNA
secondary structures, is crucial in order to explain unknown biological operations. Recently …

Syntactic Pattern Recognition for the Prediction of L-Type Pseudoknots in RNA

C Koroulis, E Makris, A Kolaitis, P Tsanakas… - Applied Sciences, 2023 - mdpi.com
The observation and analysis of RNA molecules have proved crucial for the understanding
of various processes in nature. Scientists have mined knowledge and drawn conclusions …

An intelligent grammar-based platform for RNA H-type pseudoknot prediction

E Makris, A Kolaitis, C Andrikos, V Moulos… - … Conference on Artificial …, 2022 - Springer
Predicting the secondary structure of RNA sequences has been proved quite a challenging
research field for bioinformatics. Predicting structures that encapsulate the pseudoknot motif …

Knotify_V2. 0: Deciphering RNA Secondary Structures with H-Type Pseudoknots and Hairpin Loops

A Kolaitis, E Makris, AA Karagiannis, P Tsanakas… - Genes, 2024 - mdpi.com
Accurately predicting the pairing order of bases in RNA molecules is essential for
anticipating RNA secondary structures. Consequently, this task holds significant importance …

[HTML][HTML] Grammar-Based Computational Framework for Predicting Pseudoknots of K-Type and M-Type in RNA Secondary Structures

C Pavlatos - Eng, 2024 - mdpi.com
Understanding the structural intricacies of RNA molecules is essential for deciphering
numerous biological processes. Traditionally, scientists have relied on experimental …

Conditioning and robustness of RNA Boltzmann sampling under thermodynamic parameter perturbations

E Rogers, D Murrugarra, C Heitsch - Biophysical journal, 2017 - cell.com
Understanding how RNA secondary structure prediction methods depend on the underlying
nearest-neighbor thermodynamic model remains a fundamental challenge in the field …