Enrichment of oral-derived bacteria in inflamed colorectal tumors and distinct associations of Fusobacterium in the mesenchymal subtype

BS Younginger, O Mayba, J Reeder, DR Nagarkar… - Cell Reports …, 2023 - cell.com
While the association between colorectal cancer (CRC) features and Fusobacterium has
been extensively studied, less is known of other intratumoral bacteria. Here, we leverage …

Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence

DS Franklin, YW Chen, Y Chen, M Wittchen, A Agnew… - mBio, 2024 - journals.asm.org
Many bacteria metabolize ethanolamine as a nutrient source through cytoplasmic
organelles named bacterial microcompartments (BMCs). Here we investigated the …

Highly accurate diagnosis of pancreatic cancer by integrative modeling using gut microbiome and exposome data

Y Zhang, H Zhang, B Liu, K Ning - Iscience, 2024 - cell.com
The noninvasive detection of pancreatic ductal adenocarcinoma (PDAC) remains an
immense challenge. In this study, we proposed a robust, accurate, and noninvasive …

Development of SacB-based counterselection for efficient allelic exchange in Fusobacterium nucleatum

P Zhou, B GC, B Hu, C Wu - Microbiology Spectrum, 2024 - journals.asm.org
Fusobacterium nucleatum, prevalent in the oral cavity, is significantly linked to overall
human health. Our molecular comprehension of its role in oral biofilm formation and its …

The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization

Y El Mouali, C Tawk, KD Huang, L Amend, TR Lesker… - Cell Host & Microbe, 2024 - cell.com
The bacterium Segatella copri is a prevalent member of the human gut microbiota
associated with health and disease states. However, the intrinsic factors that determine its …