Accumulating preclinical and clinical evidence indicates that high degrees of heterogeneity
among malignant cells constitute a considerable obstacle to the success of cancer therapy …

Breast cancer is the most frequently diagnosed and fatal cancer among women worldwide.
Dairy protein-derived peptides and dairy products are important parts of the daily human diet …

We observed how a change of specific residues in LfcinB dimeric and palindromic
sequences caused a notable increase in the cytotoxic activity against CaCo-2 cells while …

This study explores the potential of antimicrobial peptides (AMPs) derived from camel milk
lactoferrin as novel agents against antibiotic-resistant pathogens. Through in silico …

Aim: Evaluate the selective cytotoxic effect of the palindromic sequence RWQWRWQWR
and its analogues obtained by replacement of L-amino acids by D-amino acids or the …

Using the van Deemter model, the efficiency of three stationary phase systems in the
analysis of a mixture of synthetic peptides was evaluated:(i) monolithic,(ii) packed, and (iii) …

Matrix effect and sample pretreatment significantly affect the percentage recovery of
peptides in biological matrices, affecting the method robustness and accuracy. To counteract …

The dimeric peptide 26 [F]:(RRWQWR F KKLG) 2-K-Ahx has exhibited a potent cytotoxic
effect against breast cancer cell lines, with position 26 (F) being the most relevant for anti …

In recent years, peptides have received increased interest in pharmaceutical, food,
cosmetics, and various other fields. The high potency, specificity, and good safety profile are …

El diseño, síntesis y evaluación de péptidos anticancerígenos es una estrategia utilizada
para la búsqueda de nuevas moléculas con potencial terapéutico para el tratamiento del …