Cancer is a hyperproliferative disorder that is usually treated by chemotherapeutic agents
that are toxic not only to tumor cells but also to normal cells, so these agents produce major …

Curcuminoids, a group of phenolic compounds isolated from the roots of Curcuma longa
(Zingiberaceae), exhibit a variety of beneficial effects on health and on events that help in …

Despite the much improved therapeutic approaches for cancer treatment that have been
developed over the past 50 years, cancer remains a major cause of mortality globally …

Evidence that curcumin may have anticancer activities has renewed interest in its potential
to prevent and treat disease. In this study, we show that curcumin-mediated rapid generation …

Lower doses of capsaicin (8-methyl-N-vanillyl-6-nonenamide) have the potential to serve as
an anticancer drug, however, due to its pungency, irritant effect, poor water solubility and …

Emodin (1, 3, 8-trihydroxy-6-methylanthraquinone) is an active herbal component
traditionally used in China for treating various ailments. Emodin exerts antiproliferative …

Diabetes increases the percentage of circulating erythrocytes exposing phosphatidylserine
(PS) at the cell surface. PS-exposing erythrocytes are recognized, bound, engulfed and …

The uremic syndrome is usually attributed to the retention of a variety of compounds as a
result of a deficient renal clearance. These retention solutes are taken to induce biochemical …

Nonenzymatic covalent adduction of glucose, or aldehydes derived from glucose or
oxidation reactions, to proteins (glycation) has been proposed as a key factor in the vascular …

Pathogenic mechanisms for essential hypertension are unclear despite striking efforts from
numerous research teams over several decades. Increased production of reactive oxygen …