Enterococci facilitate polymicrobial infections

W Xu, Y Fang, K Zhu - Trends in microbiology, 2024 - cell.com
Enterococci are ubiquitous members of the gut microbiota in human beings and animals and
are among the most important nosocomial organisms. Due to their opportunistic …

The role of C-type lectin receptor signaling in the intestinal microbiota-inflammation-cancer axis

M Li, R Zhang, J Li, J Li - Frontiers in Immunology, 2022 - frontiersin.org
As a subset of pattern recognition receptors (PRRs), C-type lectin-like receptors (CLRs) are
mainly expressed by myeloid cells as both transmembrane and soluble forms. CLRs …

Global diversity of enterococci and description of 18 previously unknown species

JA Schwartzman, F Lebreton… - Proceedings of the …, 2024 - National Acad Sciences
Enterococci are gut microbes of most land animals. Likely appearing first in the guts of
arthropods as they moved onto land, they diversified over hundreds of millions of years …

Applications of human organoids in the personalized treatment for digestive diseases

Q Wang, F Guo, Y Jin, Y Ma - Signal Transduction and Targeted …, 2022 - nature.com
Digestive system diseases arise primarily through the interplay of genetic and environmental
influences; there is an urgent need in elucidating the pathogenic mechanisms of these …

Identification of indocyanine green as a STT3B inhibitor against mushroom α-amanitin cytotoxicity

B Wang, AH Wan, Y Xu, RX Zhang, BC Zhao… - Nature …, 2023 - nature.com
The “death cap”, Amanita phalloides, is the world's most poisonous mushroom, responsible
for 90% of mushroom-related fatalities. The most fatal component of the death cap is α …

Bacteria-driven bio-therapy: from fundamental studies to clinical trials

Y Yu, S Lin, Z Chen, B Qin, Z He, M Cheng, M Sun… - Nano Today, 2023 - Elsevier
Natural bacteria have been utilized to directly maintain the human body's homeostasis for
directly or indirectly relieving diseases throughout history. With the rapid development of …

The population structure of vancomycin-resistant and -susceptible Enterococcus faecium in a low-prevalence antimicrobial resistance setting is highly influenced by …

M Al Rubaye, J Janice, JV Bjørnholt… - Microbial …, 2023 - microbiologyresearch.org
Between 2010 and 2015 the incidence of vancomycin-resistant Enterococcus faecium (VRE
fm) in Norway increased dramatically. Hence, we selected (1) a random subset of …

High prevalence and plasmidome diversity of optrA-positive enterococci in a Shenzhen community, China

Y Fu, Z Deng, Y Shen, W Wei, Q Xiang, Z Liu… - Frontiers in …, 2024 - frontiersin.org
Background The emergence of optrA, which can confer resistance to phenicols and
oxazolidinones in Enterococcus spp., poses a growing public health threat. Methods 102 …

Molecular epidemiology, phenotypic and genomic characterization of antibiotic-resistant enterococcal isolates from diverse farm animals in Xinjiang, China

W Chen, Q Wang, H Wu, P Xia, R Tian, R Li… - Science of The Total …, 2024 - Elsevier
Multidrug-resistant (MDR) bacteria in farm environments can be transferred to humans
through the food chain and occupational exposure. Enterococcus infections caused by …

Design, performance, processing, and validation of a pooled CRISPR perturbation screen for bacterial toxins

S Tian, Y Qin, Y Wu, M Dong - Nature Protocols, 2024 - nature.com
Unbiased forward genetic screens have been extensively employed in biological research
to elucidate functional genomics. In pooled clustered regularly interspaced short palindromic …