Regulation of signaling by cooperative assembly formation in mammalian innate immunity signalosomes by molecular mimics

JD Nanson, MH Rahaman, T Ve, B Kobe - Seminars in Cell & …, 2020 - Elsevier
Innate immunity pathways constitute the first line of defense against infections and cellular
damage. An emerging concept in these pathways is that signaling involves the formation of …

In silico structural homology modeling and characterization of multiple N-terminal domains of selected bacterial Tcps

M Alaidarous - PeerJ, 2020 - peerj.com
Several bacterial pathogens produce Toll/interleukin-1 receptor (TIR) domain-containing
protein homologs that are important for subverting the Toll-like receptor (TLR) signaling …

Investigation of cloning strategies for the recombinant expression of a putative immune modulator TIR domain protein from probiotic Lactobacillus casei 21/1

B Bakar, S İçier, BK Türköz - Bulletin of Biotechnology, 2020 - dergipark.org.tr
TIR domain proteins have a key role in Toll-Like Receptor (TLR) signalling pathway in
innate immunity. Bacteria can produce TIR domain proteins and those from pathogens were …