Oxidative stress implications in the affective disorders: main biomarkers, animal models relevance, genetic perspectives, and antioxidant approaches

IM Balmus, A Ciobica, I Antioch… - … medicine and cellular …, 2016 - Wiley Online Library
The correlation between the affective disorders and the almost ubiquitous pathological
oxidative stress can be described in a multifactorial way, as an important mechanism of …

Zebrafish retinal defects induced by ethanol exposure are rescued by retinoic acid and folic acid supplement

P Muralidharan, S Sarmah, JA Marrs - Alcohol, 2015 - Elsevier
Abstract Fetal Alcohol Spectrum Disorder (FASD) is caused by prenatal alcohol exposure,
producing craniofacial, sensory, motor, and cognitive defects. FASD is highly prevalent in …

Complex cardiac defects after ethanol exposure during discrete cardiogenic events in zebrafish: prevention with folic acid

S Sarmah, JA Marrs - Developmental Dynamics, 2013 - Wiley Online Library
Background: Fetal alcohol spectrum disorder (FASD) describes a range of birth defects
including various congenital heart defects (CHDs). Mechanisms of FASD‐associated CHDs …

Therapeutic effects of rocket seeds (Eruca sativa L.) against testicular toxicity and oxidative stress caused by silver nanoparticles injection in rats

N Altwaijry, TA El‐Masry, B Alotaibi… - Environmental …, 2020 - Wiley Online Library
Silver nanoparticles (AgNPs), one of the most well‐known nanomaterials, are regularly
utilized in everyday consumer products. The present study aimed to investigate the testicular …

[PDF][PDF] Developmental thyroid diseases and monoaminergic dysfunction

RG Ahmed - Advances in Applied Science Research, 2017 - researchgate.net
Thyroid hormones (THs) regulate the pre-and post-natal development, particular brain
development [1-25]. Also, THs can regulate the development of monoaminergic …

Costus root extract alleviates blood biochemical derangements of experimentally-induced hypo-and hyperthyroidism in mice

Y Bolkiny, E Tousson, A El-Atrsh… - Annual Research & …, 2019 - open.journal4submit.com
Objectives: Thyroid hormones regulate all metabolic activities; therefore, it is not amazing
that hepatic; renal dysfunctions and lipid alterations are commonly detected in patients with …

Alzheimer's disease‐related brain insulin resistance and the prospective therapeutic impact of metformin

HA Abosharaf, Y Elsonbaty, E Tousson… - Journal of …, 2024 - Wiley Online Library
Besides COVID‐19, two of the most critical outbreaks of our day are insulin resistance, type
2 diabetes mellitus (T2DM), and Alzheimer's disease (AD). Each disease's pathophysiology …

Comparison of the effect of a combination of eight micronutrients versus a standard mono preparation on sperm parameters

M Lipovac, F Bodner, M Imhof, P Chedraui - Reproductive Biology and …, 2016 - Springer
Background There are reports showing that l-carnitine alone or in combination with other
micronutrients improve sperm parameters. However, comparative studies are still lacking …

Folic acid attenuated learning and memory impairment via inhibition of oxidative damage and acetylcholinesterase activity in hypothyroid rats

S Amirahmadi, M Hosseini, S Ahmadabady… - Metabolic Brain …, 2021 - Springer
Hypothyroidism has been reported to be associated with cognitive decline. Considering the
role of folic acid (FA) in cognitive performance, the present study was designed to …

Folic acid supplement rescues ethanol-induced developmental defects in the zebrafish embryos

Q Jiang, D Lu, F Wang, Y Zhang, L Cao… - Acta Biochimica et …, 2020 - academic.oup.com
Fetal alcohol syndrome (FASD) describes a range of birth defects. Mechanisms of FASD-
associated defects are not well understood. It has great significance to investigate whether …