Notch signaling in reproduction

GE Moldovan, L Miele, AT Fazleabas - Trends in Endocrinology & …, 2021 - cell.com
The Notch signaling pathway is conserved among mammalian species and controls
proliferation, differentiation, and cell death in many organs throughout the body including the …

Notch and endometrial cancer

V Jonusiene, A Sasnauskiene - … and Cancer: Notch Signaling in Cancer, 2021 - Springer
The human endometrium is a unique, highly dynamic tissue that undergoes cyclic changes
of cell proliferation, differentiation, and death. Endometrial cancer is the most common …

[HTML][HTML] Pregnancy-associated diamine oxidase originates from extravillous trophoblasts and is decreased in early-onset preeclampsia

P Velicky, K Windsperger, K Petroczi, S Pils, B Reiter… - Scientific reports, 2018 - nature.com
Human extravillous trophoblast (EVT) invasion of the pregnant uterus constitutes a pivotal
event for the establishment of the maternal-fetal interface. Compromised EVT function …

Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility

RW Su, MR Strug, JW Jeong, L Miele… - Proceedings of the …, 2016 - National Acad Sciences
In mammalian reproduction, implantation is one of the most critical events. Failure of
implantation and the subsequent decidualization contribute to more than 75% of pregnancy …

Placental methylome analysis from a prospective autism study

DI Schroeder, RJ Schmidt, FK Crary-Dooley… - Molecular autism, 2016 - Springer
Background Autism spectrum disorders (ASD) are increasingly prevalent
neurodevelopmental disorders that are behaviorally diagnosed in early childhood. Most …

Diverse endometrial mRNA signatures during the window of implantation in patients with repeated implantation failure

C Shi, HJ Han, LJ Fan, J Guan, XB Zheng, X Chen… - Human …, 2018 - Taylor & Francis
High endometrial receptivity in the window of implantation (WOI) is essential for successful
implantation. However, a diagnostic tool with high specificity for impaired endometrial …

Notch signalling in placental development and gestational diseases

S Haider, J Pollheimer, M Knöfler - Placenta, 2017 - Elsevier
Activation of Notch signalling upon cell-cell contact of neighbouring cells controls a plethora
of cellular processes such as stem cell maintenance, cell lineage determination, cell …

Bisphenol compounds regulate decidualized stromal cells in modulating trophoblastic spheroid outgrowth and invasion in vitro

H Fan, L Jiang, YL Lee, CKC Wong… - Biology of …, 2020 - academic.oup.com
Bisphenol A (BPA) is commonly found in epoxy resins used in the manufacture of plastic
coatings in food packaging and beverage cans. There is a growing concern about BPA as a …

Wingless ligand 5a is a critical regulator of placental growth and survival

G Meinhardt, L Saleh, GR Otti, S Haider, P Velicky… - Scientific reports, 2016 - nature.com
The maternal uterine environment is likely critical for human placental morphogenesis and
development of its different trophoblast subtypes. However, factors controlling growth and …

Identification of loci associated with conception rate in primiparous Holstein cows

JN Kiser, E Clancey, JGN Moraes, J Dalton, GW Burns… - BMC genomics, 2019 - Springer
Background Subfertility is a major issue facing the dairy industry as the average US Holstein
cow conception rate (CCR) is approximately 35%. The genetics underlying the physiological …