The thioredoxin (Trx) system, which is composed of NADPH, thioredoxin reductase (TrxR),
and thioredoxin, is a key antioxidant system in defense against oxidative stress through its …

Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Peroxiredoxins (Prxs) make up an ancient family of enzymes that are the predominant
peroxidases for nearly all organisms and play essential roles in reducing hydrogen …

The gastric pathogen Helicobacter pylori induces a strong inflammatory host response, yet
the bacterium maintains long‐term persistence in the host. H. pylori combats oxidative stress …

Background & Aims Dual oxidases (DUOX) are conserved reduced nicotinamide adenine
dinucleotide phosphate oxidases that produce H 2 O 2 at the epithelial cell surface. The …

Helicobacter pylori, an oxygen-sensitive microaerophilic bacterium, contains many
antioxidant proteins, among which alkylhydroperoxide reductase (AhpC) is the most …

Cryptococcus neoformans is a fungal pathogen most commonly causing meningitis in
immunocompromised patients. Current therapies are inadequate, and novel antifungal …

Maintaining iron homeostasis is a necessity for all living organisms, as free iron augments
the generation of reactive oxygen species like superoxide anions, at the risk of subsequent …

Helicobacter pylori (H. pylori) is a highly successful human pathogen that colonizes stomach
in around 50% of the global population. The colonization of bacterium induces an …

The secretomes of a virulent Bacillus anthracis strain and of avirulent strains (cured of the
virulence plasmids pXO1 and pXO2), cultured in rich and minimal media, were studied by a …