Xmipp is an open-source software package consisting of multiple programs for processing
data originating from electron microscopy and electron tomography, designed and managed …

Recent advances in both instrumentation and image processing software have made single-
particle cryo-electron microscopy (cryo-EM) the preferred method for structural biologists to …

Macromolecular assemblies, such as protein complexes, undergo continuous structural
dynamics, including global reconfigurations critical for their function. Two fast analytical …

Cryogenic electron microscopy (cryo-EM) single-particle analysis has revolutionized the
structural analysis of icosahedral viruses, including tailed bacteriophages. In recent years …

Three-dimensional (3D) reconstruction in single-particle cryo-electron microscopy (cryo-EM)
is a significant technique for recovering the 3D structure of proteins or other biological …

Modern computers are typically heterogeneous devices—besides the standard central
processing unit (CPU), they commonly include an accelerator such as a graphics processing …

Single particle analysis (SPA) in cryo-electron microscopy (cryo-EM) is highly used to obtain
the near-atomic structure of biological macromolecules. The current methods allow users to …

Spiroplasma virus 4 (SpV4) is a bacteriophage of the Microviridae, which packages circular
ssDNA within non-enveloped T= 1 icosahedral capsids. It infects spiroplasmas, which are …

Single Particle analysis (SPA) aims to determine the three-dimensional structure of proteins
and macromolecular complexes. The current state of the art has allowed us to achieve near …

Single-particle cryo-electron microscopy (cryo-EM) has become one of the mainstream
technologies in the field of structural biology to determine the three-dimensional (3D) …