Neuroendocrinology and neurobiology of sebaceous glands

RW Clayton, EA Langan, DM Ansell… - Biological …, 2020 - Wiley Online Library
The nervous system communicates with peripheral tissues through nerve fibres and the
systemic release of hypothalamic and pituitary neurohormones. Communication between …

The prolactin gene: a paradigm of tissue‐specific gene regulation with complex temporal transcription dynamics

K Featherstone, MRH White… - Journal of …, 2012 - Wiley Online Library
Transcription of numerous mammalian genes is highly pulsatile, with bursts of expression
occurring with variable duration and frequency. The presence of this stochastic or …

Relationships between housing and management factors and clinical health events in elephants in North American zoos

KL Edwards, MA Miller, K Carlstead, JL Brown - PLoS One, 2019 - journals.plos.org
Elephants experience a number of health issues that can contribute to their well-being and
survival. In managed populations, housing conditions and management practices can …

Association of psoriasis severity with serum prolactin, thyroid hormones, and cortisol before and after treatment

RM Robati, P Toossi… - The scientific world …, 2013 - Wiley Online Library
Background. Prolactin (PRL) level is proposed to be associated with the severity of psoriasis
although the previous studies reported different results. Objective. To find the association …

Prolactin as a candidate sebotrop (h) ic hormone?

EA Langan, E Hinde, R Paus - Experimental dermatology, 2018 - Wiley Online Library
Recognised for its key role in lactation, it is less well appreciated that the neurohormone
prolactin (PRL) is actually one of the most pleiotropic hormones known. Not only does PRL …

Prolactin: A Mammalian Stress Hormone and Its Role in Cutaneous Pathophysiology

EA Langan - International Journal of Molecular Sciences, 2024 - mdpi.com
The hormone prolactin (PRL) is best recognised for its indispensable role in mammalian
biology, specifically the regulation of lactation. Bearing in mind that the mammary gland is a …

Prolactin induces the production of Th17 and Th1 cytokines/chemokines in murine Imiquimod‐induced psoriasiform skin

CS Hau, N Kanda, Y Tada, S Shibata… - Journal of the …, 2014 - Wiley Online Library
Background Prolactin (PRL) is a pituitary‐derived neuropeptide hormone that has been
suggested to promote the development of psoriasis, a Th17/Th1‐mediated inflammatory …

Serum prolactin levels in psoriasis and its association with disease activity: A case-control study

MA Keen, I Hassan - Indian journal of dermatology, 2014 - journals.lww.com
Background: Psoriasis is a T-cell-mediated autoimmune chronic skin disorder in which an
environmental factor, perhaps a viral antigen, induces T cells to produce cytokines. These …

Tumour necrosis factor alpha, interferon gamma and substance P are novel modulators of extrapituitary prolactin expression in human skin

EA Langan, S Vidali, N Pigat, W Funk, E Lisztes, T Bíró… - PloS one, 2013 - journals.plos.org
Human scalp skin and hair follicles (HFs) are extra-pituitary sources of prolactin (PRL).
However, the intracutaneous regulation of PRL remains poorly understood. Therefore we …

Exploring the role of prolactin in psoriasis

EA Langan, CEM Griffiths, R Paus - Archives of dermatological research, 2012 - Springer
Prolactin (PRL) is well recognised for its role (s) in mammary gland development and
function. Moreover, its role in skin biology, including the potent regulation of human hair …