Membranous nephropathy (MN) is a glomerular disease that can occur at all ages. In adults,
it is the most frequent cause of nephrotic syndrome. In~ 80% of patients, there is no …

Mesangial cells are stromal cells that are important for kidney glomerular homeostasis and
the glomerular response to injury. A growing body of evidence demonstrates that …

The kidney has tremendous capacity to repair after acute injury, however, pathways guiding
adaptive and fibrotic repair are poorly understood. We developed a model of adaptive and …

The field of single-cell genomics and spatial technologies is rapidly evolving and has
already provided unprecedented insights into complex tissues. Major advances have been …

Numerous genes for monogenic kidney diseases with classical patterns of inheritance, as
well as genes for complex kidney diseases that manifest in combination with environmental …

Kidney fibrosis is the final common pathway of virtually all chronic kidney diseases (CKDs)
and is therefore considered to be a promising therapeutic target for these conditions …

Kidney lifespan is a patient-oriented outcome that provides much needed context for
understanding chronic kidney disease (CKD). Nephron endowment, age-associated decline …

Acute kidney injury (AKI) is a major health issue, the outcome of which depends primarily on
damage and reparative processes of tubular epithelial cells. Mechanisms underlying AKI …

A kidney organoid is a three-dimensional (3D) cellular aggregate grown from stem cells in
vitro that undergoes self-organization, recapitulating aspects of normal renal development to …

Urine plays a great role in reflecting the physiological and pathological conditions of kidney.
Glyco-and phospho-proteins in urine are important indicator for diagnosing kidney diseases …