Advances in improvement strategies of digital nucleic acid amplification for pathogen detection

X Xiang, Y Shang, J Zhang, Y Ding, Q Wu - TrAC Trends in Analytical …, 2022 - Elsevier
Digital nucleic acid amplification technologies (dNAATs) have become an emerging platform
for pathogen detection. It is not only suitable for the absolute quantitative analysis of target …

Bipolar electrode array for multiplexed detection of prostate cancer biomarkers

Y Liu, N Zhang, JB Pan, J Song, W Zhao… - Analytical …, 2022 - ACS Publications
Owing to the characteristics of high throughput, high flexibility, and convenient separation of
the sensing and reporting reactions, the bipolar electrode (BPE) shows great potential in …

A magnetically controlled microfluidic device for concentration dependent in vitro testing of anticancer drug

VK Yadav, P Ganguly, P Mishra, S Das, D Mallick - Lab on a Chip, 2023 - pubs.rsc.org
Compartmentalizing magnetically controlled drug molecules is critical in several
bioanalytical trials and tests, such as drug screening, digital PCR, magnetic hyperthermia …

Wearable Sweat Management Technologies

L Wei, Z Li, Z Dai, L Ding, H Wei, J Li… - Advanced Materials …, 2024 - Wiley Online Library
The aging population and increasing prevalence of diseases among younger individuals
have heightened the pressing demand for wearable health monitoring devices among the …

An Integrated ddPCR Lab-on-a-Disc Device for Rapid Screening of Infectious Diseases

W Zhang, L Cui, Y Wang, Z Xie, Y Wei, S Zhu, M Nawaz… - Biosensors, 2023 - mdpi.com
Digital droplet PCR (ddPCR) is a powerful amplification technique for absolute quantification
of viral nucleic acids. Although commercial ddPCR devices are effective in the lab bench …

A universal fluorescent sensing system for pathogen determination based on loop-mediated isothermal amplification triggering dual-primer rolling circle extension

M Chen, Q He, Y Tong, Z Chen - Sensors and Actuators B: Chemical, 2021 - Elsevier
The great challenge for loop-mediated isothermal amplification (LAMP) is target-specific
detection. However, the most popular fluorogenic probe method needs complicated …

Oil-Triggered and Template-Confined Dewetting for Facile and Low-Loss Sample Digitization

N Xiong, A Wang, T Xie, T Hu, Q Chen… - ACS Applied Materials …, 2022 - ACS Publications
This paper proposes a simple and robust method for spontaneously digitizing aqueous
samples into a high-density microwell array. The method is based on an oil-triggered …

Quantitative analysis of sweat evaporation loss in epidermal microfluidic patches

L Wei, J Zhou, Z Li, H Zhu, H Wu, Y Zhu, A Liu - RSC advances, 2024 - pubs.rsc.org
Sweat analysis is identified as a promising biochemical technique for the non-invasive
assessment of human health status. Epidermal microfluidic patches are the predominant …

Bubble-free diatoms polymerase chain reaction

Y Shin, T Kwak, K Whang, Y Jo, JH Hwang… - Biosensors and …, 2023 - Elsevier
Polymerase chain reaction (PCR) in small fluidic systems not only improves speed and
sensitivity of deoxyribonucleic acid (DNA) amplification but also achieves high-throughput …

Experimental and Numerical Study of Microcavity Filling Regimes for Lab-on-a-Chip Applications

L Nagel, A Lippert, R Leonhardt, T Tolle… - arXiv preprint arXiv …, 2024 - arxiv.org
The efficient and voidless filling of microcavities is of great importance for Lab-on-a-Chip
applications. However, predicting whether microcavities will be filled or not under different …