Chemotherapy-induced peripheral neuropathy: epidemiology, pathomechanisms and treatment

J Burgess, M Ferdousi, D Gosal, C Boon… - Oncology and …, 2021 - Springer
Purpose This review provides an update on the current clinical, epidemiological and
pathophysiological evidence alongside the diagnostic, prevention and treatment approach …

Advances in toxicological research of the anticancer drug cisplatin

L Qi, Q Luo, Y Zhang, F Jia, Y Zhao… - Chemical research in …, 2019 - ACS Publications
Cisplatin is one of the most widely used chemotherapeutic agents for various solid tumors in
the clinic due to its high efficacy and broad spectrum. The antineoplastic activity of cisplatin …

Chemotherapy-induced peripheral neuropathy: where are we now?

LA Colvin - Pain, 2019 - journals.lww.com
Chemotherapy-induced peripheral neuropathy (CIPN) is a major challenge, with increasing
impact as oncological treatments, using potentially neurotoxic chemotherapy, improve …

Clinical and preclinical perspectives on Chemotherapy-Induced Peripheral Neuropathy (CIPN): a narrative review

SJL Flatters, PM Dougherty… - BJA: British Journal of …, 2017 - academic.oup.com
This review provides an update on the current clinical and preclinical understanding of
chemotherapy induced peripheral neuropathy (CIPN). The overview of the clinical syndrome …

Chemotherapy‐induced peripheral neurotoxicity: a critical analysis

SB Park, D Goldstein, AV Krishnan… - CA: a cancer journal …, 2013 - Wiley Online Library
With a 3‐fold increase in the number of cancer survivors noted since the 1970s, there are
now over 28 million cancer survivors worldwide. Accordingly, there is a heightened …

Clinical course of oxaliplatin-induced neuropathy: results from the randomized phase III trial N08CB (Alliance)

DR Pachman, R Qin, DK Seisler, EML Smith… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Given that the clinical course of oxaliplatin-induced neuropathy is not well defined,
the current study was performed to better understand clinical parameters associated with its …

Pain in cancer survivors

PA Glare, PS Davies, E Finlay, A Gulati… - Journal of clinical …, 2014 - ascopubs.org
Pain is a common problem in cancer survivors, especially in the first few years after
treatment. In the longer term, approximately 5% to 10% of survivors have chronic severe …

Mechanisms in cancer-chemotherapeutic drugs-induced peripheral neuropathy

AS Jaggi, N Singh - Toxicology, 2012 - Elsevier
Anti-cancer drugs such as vincristine, paclitaxel, oxaliplatin, cisplatin and bortezomib are
well reported to exert direct and indirect effects on sensory nerves to alter the amplitude of …

The challenges of colorectal cancer survivorship

CS Denlinger, AM Barsevick - Journal of the National Comprehensive …, 2009 - jnccn.org
With advances in treatment, colorectal cancer (CRC) is being transformed from a deadly
disease into an illness that is increasingly curable. With this transformation has come …

Clinical pattern and associations of oxaliplatin acute neurotoxicity: a prospective study in 170 patients with colorectal cancer

AA Argyriou, G Cavaletti, C Briani, R Velasco, J Bruna… - Cancer, 2013 - Wiley Online Library
BACKGROUND: The objective of the current prospective, multicenter, international study
was to trace the incidence and severity of acute oxaliplatin‐induced peripheral neuropathy …