[HTML][HTML] The IGF2BP family of RNA binding proteins links epitranscriptomics to cancer

D Ramesh-Kumar, S Guil - Seminars in Cancer Biology, 2022 - Elsevier
RNA binding proteins that act at the post-transcriptional level display a richness of
mechanisms to modulate the transcriptional output and respond to changing cellular …

Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?

JL Bell, K Wächter, B Mühleck, N Pazaitis… - Cellular and molecular …, 2013 - Springer
The insulin-like growth factor-2 mRNA-binding proteins 1, 2, and 3 (IGF2BP1, IGF2BP2,
IGF2BP3) belong to a conserved family of RNA-binding, oncofetal proteins. Several studies …

Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease

IA Qureshi, MF Mehler - Nature Reviews Neuroscience, 2012 - nature.com
Novel classes of small and long non-coding RNAs (ncRNAs) are being characterized at a
rapid pace, driven by recent paradigm shifts in our understanding of genomic architecture …

[HTML][HTML] Functional roles of non-coding Y RNAs

MP Kowalski, T Krude - The international journal of biochemistry & cell …, 2015 - Elsevier
Non-coding RNAs are involved in a multitude of cellular processes but the biochemical
function of many small non-coding RNAs remains unclear. The family of small non-coding Y …

A guide to naming human non‐coding RNA genes

RL Seal, LL Chen, S Griffiths‐Jones, TM Lowe… - The EMBO …, 2020 - embopress.org
Research on non‐coding RNA (nc RNA) is a rapidly expanding field. Providing an official
gene symbol and name to nc RNA genes brings order to otherwise potential chaos as it …

MOV10 RNA helicase is a potent inhibitor of retrotransposition in cells

JL Goodier, LE Cheung, HH Kazazian Jr - 2012 - journals.plos.org
MOV10 protein, a putative RNA helicase and component of the RNA–induced silencing
complex (RISC), inhibits retrovirus replication. We show that MOV10 also severely restricts …

Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain

C Scheckel, E Drapeau, MA Frias, CY Park, J Fak… - Elife, 2016 - elifesciences.org
Neuronal ELAV-like (nELAVL) RNA binding proteins have been linked to numerous
neurological disorders. We performed crosslinking-immunoprecipitation and RNAseq on …

Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition

JL Goodier, LE Cheung… - Nucleic acids research, 2013 - academic.oup.com
LINE1s occupy 17% of the human genome and are its only active autonomous mobile DNA.
L1s are also responsible for genomic insertion of processed pseudogenes and> 1 million …

Circulating Y-RNAs in extracellular vesicles and ribonucleoprotein complexes; implications for the immune system

TAP Driedonks, ENM Nolte-'t Hoen - Frontiers in immunology, 2019 - frontiersin.org
The exchange of extracellular vesicles (EV) between immune cells plays a role in various
immune regulatory processes. EV are nano-sized lipid bilayer-enclosed structures that …

Context-specific effects of sequence elements on subcellular localization of linear and circular RNAs

M Ron, I Ulitsky - Nature communications, 2022 - nature.com
Long RNAs vary extensively in their post-transcriptional fates, and this variation is attributed
in part to short sequence elements. We used massively parallel RNA assays to study how …