miRNAs as cornerstones in adipogenesis and obesity

SY Elkhawaga, A Ismail, EGE Elsakka, AS Doghish… - Life Sciences, 2023 - Elsevier
In recent decades, obesity has extensively emerged to the level of pandemics. It's
significantly associated with serious co-morbidities that could decrease life quality and even …

Considering sex as a biological variable in basic and clinical studies: an endocrine society scientific statement

A Bhargava, AP Arnold, DA Bangasser… - Endocrine …, 2021 - academic.oup.com
Abstract In May 2014, the National Institutes of Health (NIH) stated its intent to “require
applicants to consider sex as a biological variable (SABV) in the design and analysis of NIH …

Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats

PM Johnson, PJ Kenny - Nature neuroscience, 2010 - nature.com
We found that development of obesity was coupled with emergence of a progressively
worsening deficit in neural reward responses. Similar changes in reward homeostasis …

Dissecting components of reward:'liking','wanting', and learning

KC Berridge, TE Robinson, JW Aldridge - Current opinion in pharmacology, 2009 - Elsevier
In recent years significant progress has been made delineating the psychological
components of reward and their underlying neural mechanisms. Here we briefly highlight …

The tempted brain eats: pleasure and desire circuits in obesity and eating disorders

KC Berridge, CY Ho, JM Richard, AG DiFeliceantonio - Brain research, 2010 - Elsevier
What we eat, when and how much, all are influenced by brain reward mechanisms that
generate “liking” and “wanting” for foods. As a corollary, dysfunction in reward circuits might …

'Liking'and 'wanting'food rewards: brain substrates and roles in eating disorders

KC Berridge - Physiology & behavior, 2009 - Elsevier
What brain reward systems mediate motivational 'wanting'and hedonic 'liking'for food
rewards? And what roles do those systems play in eating disorders? This article surveys …

[HTML][HTML] Gut hormones and appetite control: a focus on PYY and GLP-1 as therapeutic targets in obesity

A De Silva, SR Bloom - Gut and liver, 2012 - ncbi.nlm.nih.gov
The global obesity epidemic has resulted in significant morbidity and mortality. However, the
medical treatment of obesity is limited. Gastric bypass is an effective surgical treatment but …

Lifestyle risk factors for oral cancer

S Petti - Oral oncology, 2009 - Elsevier
The “style of life is the unique way in which individuals try to realize their fictional final goal
and meet or avoid the three main tasks of life: work, community, love”(Alfred Adler, founder …

Dietary fibre for glycaemia control: Towards a mechanistic understanding

HD Goff, N Repin, H Fabek, D El Khoury… - … and dietary fibre, 2018 - Elsevier
One of the many functional benefits of dietary fibre when present in the human diet is its
ability to reduce the rate of absorption of glucose after consumption of high glycaemic …

Vagal and hormonal gut–brain communication: from satiation to satisfaction

HR Berthoud - Neurogastroenterology & Motility, 2008 - Wiley Online Library
Studying communication between the gut and the brain is as relevant and exciting as it has
been since Pavlov's discoveries a century ago. Although the efferent limb of this …