Psychedelics and consciousness: Distinctions, demarcations, and opportunities
Psychedelic substances produce unusual and compelling changes in conscious experience
that have prompted some to propose that psychedelics may provide unique insights …
that have prompted some to propose that psychedelics may provide unique insights …
In vivo mapping of pharmacologically induced functional reorganization onto the human brain's neurotransmitter landscape
To understand how pharmacological interventions can exert their powerful effects on brain
function, we need to understand how they engage the brain's rich neurotransmitter …
function, we need to understand how they engage the brain's rich neurotransmitter …
[HTML][HTML] From neurotransmitters to networks: Transcending organisational hierarchies with molecular-informed functional imaging
The human brain exhibits complex interactions across micro, meso-, and macro-scale
organisational principles. Recent synergistic multi-modal approaches have begun to link …
organisational principles. Recent synergistic multi-modal approaches have begun to link …
Mechanisms underlying disorders of consciousness: bridging gaps to move toward an integrated translational science
Aim In order to successfully detect, classify, prognosticate, and develop targeted therapies
for patients with disorders of consciousness (DOC), it is crucial to improve our mechanistic …
for patients with disorders of consciousness (DOC), it is crucial to improve our mechanistic …
Whole-brain modelling identifies distinct but convergent paths to unconsciousness in anaesthesia and disorders of consciousness
The human brain entertains rich spatiotemporal dynamics, which are drastically
reconfigured when consciousness is lost due to anaesthesia or disorders of consciousness …
reconfigured when consciousness is lost due to anaesthesia or disorders of consciousness …
Nonequilibrium brain dynamics as a signature of consciousness
The cognitive functions of human and nonhuman primates rely on the dynamic interplay of
distributed neural assemblies. As such, it seems unlikely that cognition can be supported by …
distributed neural assemblies. As such, it seems unlikely that cognition can be supported by …
High-order brain interactions in ketamine during rest and task: a double-blinded cross-over design using portable EEG on male participants
Ketamine is a dissociative anesthetic that induces a shift in global consciousness states and
related brain dynamics. Portable low-density EEG systems could be used to monitor these …
related brain dynamics. Portable low-density EEG systems could be used to monitor these …
Model-based whole-brain perturbational landscape of neurodegenerative diseases
The treatment of neurodegenerative diseases is hindered by lack of interventions capable of
steering multimodal whole-brain dynamics towards patterns indicative of preserved brain …
steering multimodal whole-brain dynamics towards patterns indicative of preserved brain …
A phenomenological model of whole brain dynamics using a network of neural oscillators with power-coupling
We present a general, trainable oscillatory neural network as a large-scale model of brain
dynamics. The model has a cascade of two stages-an oscillatory stage and a complex …
dynamics. The model has a cascade of two stages-an oscillatory stage and a complex …
Computational modelling in disorders of consciousness: Closing the gap towards personalised models for restoring consciousness
Disorders of consciousness are complex conditions characterised by persistent loss of
responsiveness due to brain injury. They present diagnostic challenges and limited options …
responsiveness due to brain injury. They present diagnostic challenges and limited options …