Artificial cell membrane systems for biosensing applications

T Osaki, S Takeuchi - Analytical chemistry, 2017 - ACS Publications
Biological membranes provide a physical boundary that separates the inside and outside of
a cell or organelle. They also mediate signal transduction and transport of various molecules …

Hydrodynamic shear dissipation and transmission in lipid bilayers

GJ Amador, D Van Dijk, R Kieffer… - Proceedings of the …, 2021 - National Acad Sciences
Vital biological processes, such as trafficking, sensing, and motility, are facilitated by cellular
lipid membranes, which interact mechanically with surrounding fluids. Such lipid …

[HTML][HTML] Diphytanoyl lipids as model systems for studying membrane-active peptides

S Kara, S Afonin, O Babii, AN Tkachenko… - … et Biophysica Acta (BBA …, 2017 - Elsevier
The branched chains in diphytanoyl lipids provide membranes with unique properties, such
as high chemical/physical stability, low water permeability, and no gel-to-fluid phase …

Toward realistic large-area cell membrane mimics: excluding oil, controlling composition, and including ion channels

PJ Beltramo, L Scheidegger, J Vermant - Langmuir, 2018 - ACS Publications
Capacitance measurements provide unique insights into the thickness, compressibility, and
composition of large-area membrane bilayers and are used here in addition to demonstrate …

Artificial cell membranes interfaced with optical tweezers: A versatile microfluidics platform for nanomanipulation and mechanical characterization

A Dols-Perez, V Marin, GJ Amador… - … applied materials & …, 2019 - ACS Publications
Cell lipid membranes are the site of vital biological processes, such as motility, trafficking,
and sensing, many of which involve mechanical forces. Elucidating the interplay between …

Mechanical characterization of freestanding lipid bilayers with temperature-controlled phase

AY Shourabi, R Kieffer, D de Jong, D Tam… - Soft Matter, 2024 - pubs.rsc.org
Coexistence of lipid domains in cell membranes is associated with vital biological
processes. Here, we investigate two such membranes: a multi-component membrane …

Reproducible reformation of a bilayer lipid membrane using microair bubbles

I Hashimoto, T Osaki, H Sugiura, H Mimura… - Droplet, 2023 - Wiley Online Library
Planar bilayer lipid membranes (BLMs) are widely used as models for cell membranes in
various applications, including drug discovery and biosensors. However, the nanometer …

Multilayered film for the controlled formation of freestanding lipid bilayers

H Ryu, A Fuwad, SM Kim, TJ Jeon - Colloids and Surfaces B: Biointerfaces, 2021 - Elsevier
A freestanding lipid bilayer or black lipid membrane is a powerful tool for studying ion
channels and for biophysical studies of other membrane proteins under controlled chemical …

Microfluidic formation of double-stacked planar bilayer lipid membranes by controlling the water-oil interface

K Shoji, R Kawano - Micromachines, 2018 - mdpi.com
This study reports double-stacked planar bilayer lipid membranes (pBLMs) formed using a
droplet contact method (DCM) for microfluidic formation with five-layered microchannels that …

Hydrogel-supported bilayers for studying membrane protein functions

K Shimba, Y Miyamoto, T Yagi - 2017 10th Biomedical …, 2017 - ieeexplore.ieee.org
In vitro reconstitution of membrane proteins in lipid bilayers is thought to be an effective
approach for understanding their function. Although a number of methods have been …