[HTML][HTML] Impacts of cancer therapy on male fertility: Past and present

K Duffin, RT Mitchell, MFH Brougham, G Hamer… - Molecular Aspects of …, 2024 - Elsevier
Over the past two decades, advances in cancer therapy have significantly improved survival
rates, particularly in childhood cancers. Still, many treatments pose a substantial risk for …

Harnessing the Potential of Tissue Engineering to Target Male Infertility: Insights into Testicular Regeneration

M Forouzandegan, S Sadeghmousavi, A Heidari… - Tissue and Cell, 2024 - Elsevier
Male infertility is among one of the most challenging health concerns in the world.
Traditional therapeutic interventions such as semen and testicular tissue cryopreservation …

Prior exposure to alkylating agents negatively impacts testicular organoid formation in cells obtained from childhood cancer patients

Y Cui, F Harteveld, HAM Ba Omar… - Human …, 2024 - academic.oup.com
STUDY QUESTION Can human pre-and peri-pubertal testicular cells obtained from
childhood cancer patients, previously treated with chemotherapy, form testicular organoids …

[HTML][HTML] A cross-sectional survey of healthcare professionals' knowledge, attitude and current behaviours towards female fertility preservation services within the UK

LS Kasaven, A Mitra, M Chawla, S Murugesu, N Anson… - Cancers, 2024 - mdpi.com
Simple Summary Healthcare professionals recognise the importance of fertility preservation
and their responsibility to initiate discussions. However, despite advanced training within …

[HTML][HTML] In Vitro Generation of Haploid Germ Cells from Human XY and XXY Immature Testes in a 3D Organoid System

G Galdon, NP Zarandi, NA Deebel, S Zhang, O Cornett… - Bioengineering, 2024 - mdpi.com
Increasing survival rates of children following cancer treatment have resulted in a significant
population of adult survivors with the common side effect of infertility. Additionally, the …

Spermatogenic Stem Cells: Core Biology, Defining Features, and Utilities

T Lord, JM Oatley - Molecular Reproduction and Development, 2024 - Wiley Online Library
The actions of spermatogenic stem cells (SSCs) provide the foundation for continual
spermatogenesis and regeneration of the cognate lineage following cytotoxic insult or …

The Australian New Zealand Consortium in Children, Adolescents, and Young Adults Oncofertility action plan

LS Lau, C Allingham, A Anazodo… - Pediatric blood & …, 2024 - Wiley Online Library
International and national oncofertility networks, including the US‐led Oncofertility
Consortium, FertiProtekt, and the Danish Network, have played pivotal roles in advancing …

A 12-year overview of fertility preservation practice in Nordic pediatric oncology centers

B Asadi-Azarbaijani, IC Oskam… - Journal of Cancer …, 2024 - Springer
Purpose Fertility preservation is the only option to safeguard fertility following gonadotoxic
treatments. This study aimed to provide an updated status on fertility preservation for …

Experience and andrological follow-up after testicular tissue cryopreservation

R Levade, N Rives, A Liard, L Grynberg… - Reproductive …, 2024 - Elsevier
Research question What is the experience and mid-and long-term andrological health follow-
up of (pre) pubertal males who have undergone testicular tissue freezing (TTF)? Design This …

Oncofertility in Children and Adolescents

YL Jayasinghe, E Ginsburg - Obstetrics and Gynecology …, 2024 - obgyn.theclinics.com
Fertility preservation technologies are advancing, resulting in paradigm shifts in pediatric
and adolescent medicine to reduce late effects of childhood disease on fertility. The term …