Environmental determinants of cardiovascular disease: lessons learned from air pollution

SG Al-Kindi, RD Brook, S Biswal… - Nature Reviews …, 2020 - nature.com
Air pollution is well recognized as a major risk factor for chronic non-communicable
diseases and has been estimated to contribute more to global morbidity and mortality than …

Air Pollution and Cardiovascular Disease: JACC State-of-the-Art Review

S Rajagopalan, SG Al-Kindi, RD Brook - Journal of the American College of …, 2018 - jacc.org
Abstract Fine particulate matter< 2.5 μm (PM2. 5) air pollution is the most important
environmental risk factor contributing to global cardiovascular (CV) mortality and disability …

Particulate matter air pollution: effects on the cardiovascular system

RB Hamanaka, GM Mutlu - Frontiers in endocrinology, 2018 - frontiersin.org
Air pollution is a complex mixture of gaseous and particulate components, each of which has
detrimental effects on human health. While the composition of air pollution varies greatly …

WashU epigenome browser update 2022

D Li, D Purushotham, JK Harrison, S Hsu… - Nucleic acids …, 2022 - academic.oup.com
Abstract WashU Epigenome Browser (https://epigenomegateway. wustl. edu/browser/) is a
web-based genomic data exploration tool that provides visualization, integration, and …

WashU epigenome browser update 2019

D Li, S Hsu, D Purushotham, RL Sears… - Nucleic acids …, 2019 - academic.oup.com
Abstract The WashU Epigenome Browser (https://epigenomegateway. wustl. edu/) provides
visualization, integration and analysis tools for epigenomic datasets. Since 2010, it has …

A precision environmental health approach to prevention of human disease

A Baccarelli, DC Dolinoy, CL Walker - Nature Communications, 2023 - nature.com
Human health is determined by the interaction of our environment with the genome,
epigenome, and microbiome, which shape the transcriptomic, proteomic, and metabolomic …

[PDF][PDF] Epigenetics and the exposome: DNA methylation as a proxy for health impacts of prenatal environmental exposures

ML Colwell, C Townsel, RL Petroff, JM Goodrich… - …, 2023 - academic.oup.com
The accumulation of everyday exposures can impact health across the life course, but our
understanding of such exposures is impeded by our ability to delineate the relationship …

Exposome in ischaemic heart disease: beyond traditional risk factors

RA Montone, M Camilli, C Calvieri… - European Heart …, 2024 - academic.oup.com
Ischaemic heart disease represents the leading cause of morbidity and mortality, typically
induced by the detrimental effects of risk factors on the cardiovascular system. Although …

Metals exposures and DNA methylation: current evidence and future directions

ER Elkin, C Higgins, MT Aung, KM Bakulski - Current environmental health …, 2022 - Springer
Abstract Purpose of the Review Exposure to essential and non-essential metals is
widespread. Metals exposure is linked to epigenetic, particularly DNA methylation …

Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease

JA Hollander, DA Cory-Slechta, FN Jacka… - …, 2020 - nature.com
The etiologic pathways leading to neuropsychiatric diseases remain poorly defined. As
genomic technologies have advanced over the past several decades, considerable …