Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …

WR Brown and CR Thore (2011) Neuropathology and Applied Neurobiology37, 56–74
Cerebral microvascular pathology in ageing and neurodegeneration This review of age …

Alzheimer's disease is the main cause of dementia in the elderly and begins with a subtle
decline in episodic memory followed by a more general decline in overall cognitive abilities …

Neuroinflammatory processes are a central feature of Alzheimer's disease (AD) in which
microglia are over-activated, resulting in the increased production of pro-inflammatory …

Alzheimer's disease (AD) is an age-related disorder characterized by progressive cognitive
decline and dementia. Alzheimer's disease is an increasingly prevalent disease with 5.3 …

The development of the nervous and vascular systems constitutes primary events in the
evolution of the animal kingdom; the former provides electrical stimuli and coordination …

Vascular endothelial growth factor (VEGF) is a hypoxia-inducible angiogenic peptide with
recently identified neurotrophic effects. Because some neurotrophic factors can protect …

Angiogenesis—the growth of new blood vessels—is a crucial force for shaping the nervous
system and protecting it from disease. Recent advances have improved our understanding …

Both blood vessels and nerves are guided to their target. Vascular endothelial growth factor
(VEGF) A is a key signal in the induction of vessel growth (a process termed angiogenesis) …

Age is a common risk factor for Alzheimer's disease (AD) and age-related macular
degeneration (AMD). Because of the increasing age of the population, these two age-related …