Fifty years of HLA-associated type 1 diabetes risk: history, current knowledge, and future directions

JA Noble - Frontiers in Immunology, 2024 - frontiersin.org
More than 50 years have elapsed since the association of human leukocyte antigens (HLA)
with type 1 diabetes (T1D) was first reported. Since then, methods for identification of HLA …

Evaluation of teplizumab's efficacy and safety in treatment of type 1 diabetes mellitus: A systematic review and meta-analysis

XL Ma, D Ge, XJ Hu - World Journal of Diabetes, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Islets of Langerhans beta cells diminish in autoimmune type 1 diabetes
mellitus (T1DM). Teplizumab, a humanized anti-CD3 monoclonal antibody, may help T1DM …

Safety of teplizumab in patients with high-risk for diabetes mellitus type 1: A systematic review

V Buddhavarapu, G Dhillon, H Grewal… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND The incidence of diabetes mellitus type 1 (DM1) has been rising worldwide
because of improvements in diagnostic techniques and improved access to care in countries …

Baihu Jia Renshen Decoction may improve skeletal muscle and adipose tissue functions of type I diabetic rats by affecting pancreatic β-cell function

S Chu, D Liu, H Zhao, L Liu, J Li, G Wang, X Liu, H Li - Genes & Genomics, 2024 - Springer
Abstract Background Baihu Jia Renshen Decoction (BJRD) is used for diabetes mellitus
(DM) management in clinics. Objective To elucidate the potential mechanism of BJRD in …

Flavonoids in Astragali Radix Functions as Regulators of CDK2, VEGFA and MYC in Osteoporosis and Type 1 Diabetes Mellitus

Z Liu, X Zuo, Y Cai, Y Zuo, K Ma, S Wu… - Letters in Drug …, 2024 - benthamdirect.com
Background People with type 1 diabetes mellitus (T1DM) are significantly more likely to
have osteoporosis (OP). Astragali Radix is a Chinese herbal medicine containing various …

Avaliação da expressão gênica e proteica do Receptor Ativado por Proliferador de Peroxissoma Gama em modelo murino de Diabetes Mellitus e Periodontite

MA Rimachi Hidalgo - 2024 - repositorio.unesp.br
RESUMO É cada vez mais frequente encontrar pacientes afetados pela combinação de
Diabetes Mellitus tipo 2 (DM2) e Periodontite (P). Ambas as patologias elicitam a resposta …

[图书][B] Fishing for Small Molecules to Treat Diabetes, from a Beta Cell Perspective

L Ren - 2023 - search.proquest.com
Maintenance of glucose homeostasis necessitates a precise control of insulin secretion.
Pancreatic β cells sense fluctuation of blood glucose and secret insulin in response …

Teplizumab: uma promessa terapêutica no tratamento e prevenção da diabetes mellitus tipo 1

MMC Pereira - 2024 - ubibliorum.ubi.pt
Introdução: A diabetes mellitus tipo 1 (DM1) é uma doença autoimune caracterizada pela
destruição das células beta do pâncreas, o que, por sua vez, resulta numa diminuição da …

Has Teplizumab availability changed laboratory testing for type 1 diabetes?

JP Carson - myadlm.org
Type 1 diabetes (T1D) is often diagnosed by clinical symptoms and lab tests, many times
after a life-threatening ketoacidosis event, especially in children and adolescents. However …