[HTML][HTML] Secondary metabolites and biodiversity of actinomycetes

MSM Selim, SA Abdelhamid, SS Mohamed - Journal of Genetic …, 2021 - Elsevier
Background The ability to produce microbial bioactive compounds makes actinobacteria
one of the most explored microbes among prokaryotes. The secondary metabolites of …

[HTML][HTML] Pharmaceutically active secondary metabolites of marine actinobacteria

P Manivasagan, J Venkatesan, K Sivakumar… - Microbiological …, 2014 - Elsevier
Marine actinobacteria are one of the most efficient groups of secondary metabolite
producers and are very important from an industrial point of view. Many representatives of …

Fe (II)/α-ketoglutarate-dependent hydroxylases and related enzymes

RP Hausinger - Critical reviews in biochemistry and molecular …, 2004 - Taylor & Francis
Fe (II)/α-ketoglutarate (αKG)-dependent hydroxylases catalyze an amazing diversity of
reactions that result in protein side-chain modifications, repair of alkylated DNA/RNA …

Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new …

HJ Sofia, G Chen, BG Hetzler… - Nucleic acids …, 2001 - academic.oup.com
A novel protein superfamily with over 600 members was discovered by iterative profile
searches and analyzed with powerful bioinformatics and information visualization methods …

Natural product drug discovery in the genomic era: realities, conjectures, misconceptions, and opportunities

RH Baltz - Journal of Industrial Microbiology and Biotechnology, 2019 - academic.oup.com
Natural product discovery from microorganisms provided important sources for antibiotics,
anti-cancer agents, immune-modulators, anthelminthic agents, and insecticides during a …

[图书][B] Anticancer agents from natural products

GM Cragg, DGI Kingston, DJ Newman - 2005 - taylorfrancis.com
Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

The radical SAM superfamily

PA Frey, AD Hegeman, FJ Ruzicka - Critical reviews in …, 2008 - Taylor & Francis
The radical S-adenosylmethionine (SAM) superfamily currently comprises more than 2800
proteins with the amino acid sequence motif CxxxCxxC unaccompanied by a fourth …

The shikimate pathway: gateway to metabolic diversity

VV Shende, KD Bauman, BS Moore - Natural Product Reports, 2024 - pubs.rsc.org
Covering: 1997 to 2023 The shikimate pathway is the metabolic process responsible for the
biosynthesis of the aromatic amino acids phenylalanine, tyrosine, and tryptophan. Seven …

Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis

CJ Thibodeaux, W Chang, H Liu - Chemical reviews, 2012 - ACS Publications
Cyclopropane, epoxide, and aziridine groups are three-membered ring structural elements
found in a wide variety of natural products, some of which are depicted in Figure 1. 1 The …

[HTML][HTML] RETRACTED: Marine actinobacterial metabolites: Current status and future perspectives

P Manivasagan, J Venkatesan, K Sivakumar… - Microbiological …, 2013 - Elsevier
Marine actinobacteriology is one of the major emerging areas of research in tropics. Marine
actinobacteria are the most economically as well as biotechnologically valuable …