Metal toxicity links to Alzheimer's disease and neuroinflammation

TJ Huat, J Camats-Perna, EA Newcombe… - Journal of molecular …, 2019 - Elsevier
As the median age of the population increases, the number of individuals with Alzheimer's
disease (AD) and the associated socio-economic burden are predicted to worsen. While …

Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides …

CC Willhite, NA Karyakina, RA Yokel… - Critical reviews in …, 2014 - Taylor & Francis
Aluminum (Al) is a ubiquitous substance encountered both naturally (as the third most
abundant element) and intentionally (used in water, foods, pharmaceuticals, and vaccines); …

Oxidative stress and mitochondrial dysfunction in aluminium neurotoxicity and its amelioration: a review

V Kumar, KD Gill - Neurotoxicology, 2014 - Elsevier
Aluminium is light weight and toxic metal present ubiquitously on earth which has gained
considerable attention due to its neurotoxic effects. The widespread use of products made …

Acute aluminum chloride toxicity revisited: Study on DNA damage and histopathological, biochemical and neurochemical alterations in rat brain

L Liaquat, S Sadir, Z Batool, S Tabassum, S Shahzad… - Life sciences, 2019 - Elsevier
Aims Due to rapid increase in industrialization in the last few years, use of aluminum (Al)
and its alloys have been increased in different industrial fields. Ample evidence supports the …

Aluminum and Alzheimer's disease

MT Colomina, F Peris-Sampedro - Neurotoxicity of metals, 2017 - Springer
Aluminum (Al) is one of the most extended metals in the Earth's crust. Its abundance,
together with the widespread use by humans, makes Al-related toxicity particularly relevant …

Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease

F Morroni, A Tarozzi, G Sita, C Bolondi, JMZ Moraga… - Neurotoxicology, 2013 - Elsevier
Parkinson's disease (PD) is characterized by the selective loss of dopaminergic nigrostriatal
neurons, which leads to disabling motor disturbances. Sulforaphane (SFN), found in …

Rutin protects dopaminergic neurons from oxidative stress in an animal model of Parkinson's disease

M Moshahid Khan, SS Raza, H Javed, A Ahmad… - Neurotoxicity …, 2012 - Springer
This study was undertaken to investigate the neuroprotective effects of rutin (vitamin P) on 6-
hydroxydopamine (6-OHDA)-induced Parkinson's disease (PD) in rats. Oxidative stress and …

Molecular mechanisms of aluminum neurotoxicity: Update on adverse effects and therapeutic strategies

AV Skalny, M Aschner, Y Jiang, YG Gluhcheva… - Advances in …, 2021 - Elsevier
Recent studies have demonstrated that brain may be considered as the target for aluminium
(Al) toxicity, resulting in development of neurodegenerative and neurodevelopmental …

[HTML][HTML] Aluminum overload increases oxidative stress in four functional brain areas of neonatal rats

CY Yuan, YJ Lee, GSW Hsu - Journal of biomedical science, 2012 - Springer
Abstract Background Higher aluminum (Al) content in infant formula and its effects on
neonatal brain development are a cause for concern. This study aimed to evaluate the …

[HTML][HTML] Concentration-regulated multi-color fluorescent carbon dots for the detection of rifampicin, morin and Al3+

X Tang, Y Zhao, H Yu, S Cui, H Temple… - Materials Today …, 2023 - Elsevier
Carbon dots have many new and interesting phenomena, and the concentration dependent
luminescence wavelength is an intriguing one. Herein, nitrogen-sulfur co-doped carbon dots …