Numerous bacteria utilize molecular communication systems referred to as quorum sensing
(QS) to synchronize the expression of certain genes regulating, among other aspects, the …

The approximate 30 extant invertebrate phyla have diversified along separate evolutionary
trajectories for hundreds of millions of years. Although recent work understandably has …

Acinetobacter baumannii has emerged as an important and problematic human pathogen
as it is the causative agent of several types of infections including pneumonia, meningitis …

Koch's postulates were derived from Robert Koch's work on infectious diseases, such as
anthrax and tuberculosis, which still engage us to this day. These guidelines were an …

Innate immunity is an ancient and conserved defense mechanism. Although host responses
toward various pathogens have been delineated, how these responses are orchestrated in a …

The nematode Caenorhabditis elegans is emerging as a facile and economical model host
for the study of evolutionarily conserved mechanisms of microbial pathogenesis and innate …

The maintenance of cellular and organismal homeostasis in the face of changes in the
environment is essential for survival. Pathogenic microorganisms represent one type of …

Simple model organisms that are amenable to comprehensive experimental analysis can be
used to elucidate the molecular genetic architecture of complex traits. They can thereby …

Staphylococcus epidermidis and Staphylococcus aureus are leading causes of hospital-
acquired infections that have become increasingly difficult to treat due to the prevalence of …

In response to infection, Caenorhabditis elegans produces an array of antimicrobial
proteins. To understand the C. elegans immune response, we have investigated the …