Mass cytometry has revolutionized immunophenotyping, particularly in exploratory settings
where simultaneous breadth and depth of characterization of immune populations is needed …

Fluorescence microscopy has become a critical tool for researchers to understand biological
processes at the cellular level. Micrographs from fixed and live-cell imaging procedures …

Immunofluorescence staining is the most frequently applied technique to detect and
visualize various molecules in biological samples. Many protocols can be found in the …

Formalin fixation and paraffin‐embedding (FFPE) is the most common method to preserve
human tissue for clinical diagnosis, and FFPE archives represent an invaluable resource for …

Multiplexing, labeling for multiple immunostains in the very same cell or tissue section in
situ, has raised considerable interest. The methods proposed include the use of labeled …

Glycosylated proteins account for a majority of the posttranslation modifications of cell
surface, secreted, and circulating proteins. Within the tumor microenvironment, the presence …

Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of
function of the protein dystrophin. This protein contributes to the stabilisation of striated cells …

Pathogenic α-synuclein (α-syn) is a prion-like protein that drives the pathogenesis of Lewy
Body Dementia (LBD) and Parkinson's Disease (PD). To target pathogenic α-syn preformed …

The combination of optical tissue transparency with immunofluorescence allows the
molecular characterization of biological tissues in 3D. However, adult human organs are …

Over recent years, human autoantibodies targeting myelin oligodendrocyte glycoprotein
(MOG Ab) have been associated with monophasic and relapsing central nervous system …