Global and multi-national prevalence of fungal diseases—estimate precision

F Bongomin, S Gago, RO Oladele, DW Denning - Journal of fungi, 2017 - mdpi.com
Fungal diseases kill more than 1.5 million and affect over a billion people. However, they are
still a neglected topic by public health authorities even though most deaths from fungal …

Chronic obstructive pulmonary disease exacerbation fundamentals: diagnosis, treatment, prevention and disease impact

M MacLeod, A Papi, M Contoli, B Beghé, BR Celli… - …, 2021 - Wiley Online Library
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …

Impact and prevention of severe exacerbations of COPD: a review of the evidence

DMG Halpin, M Miravitlles, N Metzdorf… - International journal of …, 2017 - Taylor & Francis
Severe exacerbations of COPD, ie, those leading to hospitalization, have profound clinical
implications for patients and significant economic consequences for society. The prevalence …

Procalcitonin to guide antibiotic administration in COPD exacerbations: a meta-analysis

AG Mathioudakis… - European …, 2017 - Eur Respiratory Soc
Challenges in the differentiation of the aetiology of acute exacerbations of chronic
obstructive pulmonary disease (AECOPD) have led to significant overuse of antibiotics …

[HTML][HTML] Delivering on antimicrobial resistance agenda not possible without improving fungal diagnostic capabilities

DW Denning, DS Perlin, EG Muldoon… - Emerging infectious …, 2017 - ncbi.nlm.nih.gov
Antimicrobial resistance, a major public health concern, largely arises from excess use of
antibiotic and antifungal drugs. Lack of routine diagnostic testing for fungal diseases …

[HTML][HTML] Acute exacerbations of chronic obstructive pulmonary disease with low serum procalcitonin values do not benefit from antibiotic treatment: a prospective …

JX Wang, SM Zhang, XH Li, Y Zhang, ZY Xu… - International Journal of …, 2016 - Elsevier
Objective The majority of patients with acute exacerbations of chronic obstructive pulmonary
disease (AECOPD) have low serum procalcitonin (PCT) values. The aim of this study was to …

In-hospital antibiotic use for severe chronic obstructive pulmonary disease exacerbations: a retrospective observational study

A Vanoverschelde, C Van Hoey, F Buyle… - BMC Pulmonary …, 2023 - Springer
Background The use of antibiotics in mild to severe acute exacerbations of chronic
obstructive pulmonary disease (COPD) remains controversial. Aim To explore in-hospital …

Procalcitonin-guided use of antibiotic in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease: a randomized clinical trial

W Sheng, L Huang, X Gu, Y Wang, M Jiang… - Clinical Microbiology …, 2024 - Elsevier
Objectives The objectives of this study are to analyse the effect and safety of procalcitonin
(PCT)-guided antibiotic therapy in patients with acute exacerbation of chronic obstructive …

Effects of air pollution on acute exacerbation of chronic obstructive pulmonary disease: a descriptive retrospective study (pol-AECOPD)

JA Morantes-Caballero… - International Journal of …, 2019 - Taylor & Francis
Purpose Acute exacerbation of COPD (AECOPD) is among the most frequent causes for
hospital admission, causing morbidity and mortality. Infection is the most frequent cause …

Development and relevance of hypercapnia in COPD

C Dave, S Wharton, R Mukherjee… - Canadian respiratory …, 2021 - Wiley Online Library
Background. Identification of patients who may become hypercapnic, or develop acidotic
hypercapnic respiratory failure (AHRF), is important in chronic obstructive pulmonary …