Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration

H Wei, J Cui, K Lin, J Xie, X Wang - Bone research, 2022 - nature.com
Bone defects combined with tumors, infections, or other bone diseases are challenging in
clinical practice. Autologous and allogeneic grafts are two main traditional remedies, but …

Review of a new bone tumor therapy strategy based on bifunctional biomaterials

J Liao, R Han, Y Wu, Z Qian - Bone research, 2021 - nature.com
Bone tumors, especially those in osteosarcoma, usually occur in adolescents. The standard
clinical treatment includes chemotherapy, surgical therapy, and radiation therapy …

Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli‐responsive, toxicity, immunogenicity, and clinical translation

E Sharifi, A Bigham, S Yousefiasl, M Trovato… - Advanced …, 2022 - Wiley Online Library
Cancer is one of the top life‐threatening dangers to the human survival, accounting for over
10 million deaths per year. Bioactive glasses have developed dramatically since their …

2D MXene‐integrated 3D‐printing scaffolds for augmented osteosarcoma phototherapy and accelerated tissue reconstruction

S Pan, J Yin, L Yu, C Zhang, Y Zhu, Y Gao… - Advanced …, 2020 - Wiley Online Library
The residual of malignant tumor cells and lack of bone‐tissue integration are the two critical
concerns of bone‐tumor recurrence and surgical failure. In this work, the rational integration …

[HTML][HTML] The role of rare earth elements in bone tissue engineering scaffolds-a review

J Gao, L Feng, B Chen, B Fu, M Zhu - Composites Part B: Engineering, 2022 - Elsevier
Rare earth elements (REEs) have gained spotlights with particular features to promote bone
regeneration. Therefore, the introduction of appropriate REEs into bone tissue engineering …

The journey of multifunctional bone scaffolds fabricated from traditional toward modern techniques

A Bigham, F Foroughi, E Rezvani Ghomi… - Bio-Design and …, 2020 - Springer
As a bone scaffold, meeting all basic requirements besides dealing with other bone-related
issues—bone cancer and accelerated regeneration—is not expected from traditional …

Nanoscale materials-based platforms for the treatment of bone-related diseases

X Zhang, S Koo, JH Kim, X Huang, N Kong, L Zhang… - Matter, 2021 - cell.com
Owing to the high density of bone tissue and the complex and highly hierarchical structure,
drugs used for the treatment of bone-related diseases are often not effectively concentrated …

3D printing of metal-organic framework nanosheets-structured scaffolds with tumor therapy and bone construction

W Dang, B Ma, B Li, Z Huan, N Ma, H Zhu… - …, 2020 - iopscience.iop.org
After surgical resection for a bone tumor, the uncleared bone tumor cells can multiply and
cause recurrence of the bone tumor. It is worthwhile to design a scaffold that kills the …

Nb2C MXene-Functionalized Scaffolds Enables Osteosarcoma Phototherapy and Angiogenesis/Osteogenesis of Bone Defects

J Yin, S Pan, X Guo, Y Gao, D Zhu, Q Yang, J Gao… - Nano-Micro Letters, 2021 - Springer
Early surgical resection and chemotherapy of bone cancer are commonly used in the
treatment of bone tumor, but it is still highly challenging to prevent recurrence and fill the …

[HTML][HTML] NIR light-assisted phototherapies for bone-related diseases and bone tissue regeneration: A systematic review

Z Wan, P Zhang, L Lv, Y Zhou - Theranostics, 2020 - ncbi.nlm.nih.gov
Recently, the rapid development of biomaterials has induced great interest in the precisely
targeted treatment of bone-related diseases, including bone cancers, infections, and …