New microfluidic systems for whole organism analysis and experimentation are catalyzing
biological breakthroughs across many fields, from human health to fundamental biology …

Comprehensively resolving neuronal identities in whole-brain images is a major challenge.
We achieve this in C. elegans by engineering a multicolor transgene called NeuroPAL (a …

Background There is a limited understanding of odor-taste interactions at the molecular
levels about how these interactions influence flavor perception. Microfluidic technology used …

Animal behavior is shaped both by evolution and by individual experience. Parallel brain
pathways encode innate and learned valences of cues, but the way in which they are …

Animals exhibit different behavioral responses to the same sensory cue depending on their
internal state at a given moment. How and where in the brain are sensory inputs combined …

In olfactory systems, convergence of sensory neurons onto glomeruli generates a map of
odorant receptor identity. How glomerular maps relate to sensory space remains unclear …

Highlights•Drosophila larva enables combining comprehensive synapse resolution
connectivity maps with cellular-resolution activity maps and behavior maps.•This approach …

Modern recording technologies now enable simultaneous recording from large numbers of
neurons. This has driven the development of new statistical models for analyzing and …

Multicellular model organisms, such as Drosophila melanogaster (fruit fly), are frequently
used in a myriad of biological research studies due to their biological significance and …

Studying chemosensory processing desires precise chemical cue presentation, behavioral
response monitoring, and large-scale neuronal activity recording. Here we present Fish-on …